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The compound database

Peptide Databasepage 3

264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.

FDA-approved
90
FDA-approved
Awaiting FDA
8
Awaiting FDA
No lawful pathway
166
No lawful pathway
73–90 of 90 · FDA ApprovedClear filters
  1. 073

    Melphalan Flufenamide (Pepaxto)

    Melphalan flufenamide (melflufen, Pepaxto) is a first-in-class peptide-drug conjugate that links the alkylating agent melphalan to a dipeptide carrier. It…

    Oncology · FDA Approved · Intravenous

    FDA-approved
  2. 074

    Cholecystokinin (CCK)

    Cholecystokinin (CCK) is a family of peptide hormones and neurotransmitters derived from proCCK; the main circulating forms are CCK-58, CCK-33, CCK-22, and…

    Gastrointestinal · FDA Approved · Intravenous

    FDA-approved
  3. 075

    Polymyxin B

    Polymyxin B is a cyclic lipopeptide antibiotic consisting of a heptapeptide ring and a tripeptide side chain acylated with a fatty acid tail. It binds…

    Antimicrobial · FDA Approved · Intravenous, Intrathecal, Topical

    FDA-approved
  4. 076

    Colistin (Polymyxin E)

    Colistin, also known as polymyxin E, is a cyclic polypeptide antibiotic structurally similar to polymyxin B. It disrupts the Gram-negative outer membrane by…

    Antimicrobial · FDA Approved · Intravenous, Intramuscular, Inhalation

    FDA-approved
  5. 077

    PTH (1-34) Analogs

    This class includes teriparatide, which corresponds to the 34 N-terminal amino acids of human parathyroid hormone, and abaloparatide, which the FDA label…

    Bone · FDA Approved · Subcutaneous injection

    FDA-approved
  6. 078

    Sclerostin Antibodies (Romosozumab)

    Romosozumab is a humanized monoclonal antibody that binds and inhibits sclerostin, a glycoprotein produced by osteocytes that negatively regulates Wnt…

    Bone · FDA Approved · Subcutaneous injection

    FDA-approved
  7. 079

    BMP-2 (Bone Morphogenetic Protein-2)

    BMP-2 is a member of the transforming growth factor-beta superfamily and functions as a homodimeric protein. It binds type I and type II serine and threonine…

    Bone · FDA Approved · Surgical implantation

    FDA-approved
  8. 080

    BMP-7 (Osteogenic Protein-1)

    BMP-7, also known as osteogenic protein-1, is a bone morphogenetic protein with a mature homodimeric structure. Like other BMPs it signals through serine and…

    Bone · FDA Approved · Surgical implantation

    FDA-approved
  9. 081

    Gonadotropin Releasing Hormone (GnRH) Agonists

    Gonadotropin-releasing hormone agonists are synthetic analogues of native GnRH that initially stimulate and then, with continuous exposure, downregulate…

    Longevity · FDA Approved · Subcutaneous injection, Intramuscular injection, Subcutaneous implant, Intranasal

    FDA-approved
  10. 082

    Mitochondrial-Targeted Peptides (MTP)

    Mitochondrial-targeted peptides are short synthetic sequences designed to localize to mitochondria and limit oxidative damage and organelle dysfunction. The…

    Longevity · FDA Approved · Subcutaneous injection, Intravenous

    FDA-approved
  11. 083

    Nafarelin (Synarel)

    Nafarelin is a synthetic decapeptide analogue of gonadotropin-releasing hormone with substitutions that enhance receptor affinity and metabolic stability.…

    Reproductive · FDA Approved · Intranasal

    FDA-approved
  12. 084

    Choriogonadotropin Alfa (Ovidrel)

    Choriogonadotropin alfa is a recombinant human chorionic gonadotropin produced in Chinese hamster ovary cells. The heterodimeric glycoprotein binds the LH/hCG…

    Reproductive · FDA Approved · Subcutaneous injection

    FDA-approved
  13. 085

    Follitropin Alfa (Gonal-F)

    Follitropin alfa is a recombinant human follicle-stimulating hormone produced in Chinese hamster ovary cells, a heterodimeric glycoprotein of an alpha and a…

    Reproductive · FDA Approved · Subcutaneous injection

    FDA-approved
  14. 086

    Menotropin (Menopur)

    Menotropin is a purified preparation of human menopausal gonadotropins extracted from the urine of postmenopausal women, containing both follicle-stimulating…

    Reproductive · FDA Approved · Subcutaneous injection, Intramuscular injection

    FDA-approved
  15. 087

    Cetrorelix (Cetrotide) Analog

    Cetrorelix is a synthetic decapeptide analogue of gonadotropin-releasing hormone that acts as a competitive GnRH receptor antagonist. By blocking pituitary…

    Reproductive · FDA Approved · Subcutaneous injection

    FDA-approved
  16. 088

    Peginesatide (Omontys)

    Peginesatide is a synthetic pegylated peptide-based erythropoiesis-stimulating agent that activates the erythropoietin receptor despite having no sequence…

    Hematology · FDA Approved · Intravenous, Subcutaneous injection

    FDA-approved
  17. 089

    Eltrombopag Peptide Mimetics

    Eltrombopag is an orally active, small-molecule, non-peptide thrombopoietin receptor agonist. Although it is not itself a peptide, it activates thrombopoietin…

    Hematology · FDA Approved · Oral

    FDA-approved
  18. 090

    DOTATATE (Ga-68)

    Gallium-68 DOTATATE is a radiolabeled somatostatin analogue consisting of the octapeptide Tyr3-octreotate conjugated to the macrocyclic chelator DOTA, which…

    Diagnostic · FDA Approved · Intravenous

    FDA-approved

Index · all 264 peptides, A–Z

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