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The compound database

Peptide Database

264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.

FDA-approved
90
FDA-approved
Awaiting FDA
8
Awaiting FDA
No lawful pathway
166
No lawful pathway
1–19 of 19 · DermatologyClear filters
  1. 001

    Afamelanotide (Scenesse)

    A synthetic 13-amino acid analog of alpha-melanocyte-stimulating hormone (alpha-MSH), [Nle4-D-Phe7]-alpha-MSH, with norleucine at position 4 and…

    Dermatology · FDA Approved · Subcutaneous implant

    FDA-approved
  2. 002

    Argireline (Acetyl Hexapeptide-8)

    Argireline is a synthetic six amino acid peptide (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2) patterned on the N-terminal end of the SNAP-25 protein and designed to mimic…

    Dermatology · Investigational · Topical

    No lawful pathway
  3. 003

    Matrixyl (Palmitoyl Pentapeptide-4)

    Matrixyl is a lipopeptide composed of the pentapeptide sequence Lys-Thr-Thr-Lys-Ser (KTTKS) attached to palmitic acid to improve skin delivery. In vitro work…

    Dermatology · Investigational · Topical

    No lawful pathway
  4. 004

    Matrixyl 3000

    Matrixyl 3000 is a proprietary combination of two lipopeptides, palmitoyl tripeptide-1 (Pal-GHK) and palmitoyl tetrapeptide-7 (Pal-GQPR), marketed to support…

    Dermatology · Investigational · Topical

    No lawful pathway
  5. 005

    Matrixyl Synthe'6 (Palmitoyl Tripeptide-38)

    Palmitoyl tripeptide-38 is a synthetic lipopeptide described as a matrix-repair peptide for photoaged skin. Its supplier markets it as stimulating synthesis of…

    Dermatology · Investigational · Topical

    No lawful pathway
  6. 006

    SYN-AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate)

    SYN-AKE is a synthetic dipeptide derivative modeled on waglerin-1, a peptide from Temple viper venom that blocks the adult muscle-type nicotinic acetylcholine…

    Dermatology · Investigational · Topical

    No lawful pathway
  7. 007

    SNAP-8 (Acetyl Octapeptide-3)

    SNAP-8 is an elongated derivative of Argireline, consisting of eight amino acids (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2) intended to mimic the SNAP-25…

    Dermatology · Investigational · Topical

    No lawful pathway
  8. 008

    Leuphasyl (Pentapeptide-18)

    Leuphasyl is a synthetic pentapeptide (Tyr-D-Ala-Gly-Phe-Leu) modeled on the N-terminal sequence of enkephalin. It is described as a neuromodulatory peptide…

    Dermatology · Investigational · Topical

    No lawful pathway
  9. 009

    Vialox (Pentapeptide-3)

    Vialox (pentapeptide-3) is a synthetic pentapeptide marketed as a topical agent that interferes with acetylcholine receptor activation to reduce muscle…

    Dermatology · Research Phase · Topical

    No lawful pathway
  10. 010

    Rigin (Palmitoyl Tetrapeptide-7)

    Rigin is the tetrapeptide Gly-Gln-Pro-Arg, originally identified as a tuftsin-like fragment of human immunoglobulin G with phagocytosis-stimulating activity…

    Dermatology · Investigational · Topical

    No lawful pathway
  11. 011

    Biopeptide CL (Palmitoyl Tripeptide-5)

    Palmitoyl Tripeptide-5 is a synthetic lipopeptide consisting of a tripeptide sequence conjugated to palmitic acid to improve skin delivery. Its suppliers…

    Dermatology · Investigational · Topical

    No lawful pathway
  12. 012

    Decorinyl (Tripeptide-10 Citrulline)

    Decorinyl (tripeptide-10 citrulline) is a synthetic tetrapeptide designed to mimic the collagen-binding sites of decorin, a small proteoglycan that regulates…

    Dermatology · Investigational · Topical

    No lawful pathway
  13. 013

    Haloxyl (Chrysin + Palmitoyl Peptides)

    Haloxyl is a proprietary cosmetic ingredient combining chrysin, a naturally occurring flavone, with palmitoyl peptides, marketed to reduce under-eye dark…

    Dermatology · Research Phase · Topical

    No lawful pathway
  14. 014

    Eyeseryl (Acetyl Tetrapeptide-5)

    Acetyl Tetrapeptide-5 is a synthetic tetrapeptide modified with an acetyl group to improve stability. It is marketed to reduce under-eye puffiness and fluid…

    Dermatology · Research Phase · Topical

    No lawful pathway
  15. 015

    Trylagen (Tripeptide-10 Complex)

    Trylagen is a proprietary cosmetic complex that incorporates Tripeptide-10 Citrulline along with other peptide and protein components, marketed to support…

    Dermatology · Research Phase · Topical

    No lawful pathway
  16. 016

    Myristoyl Pentapeptide-17

    Myristoyl Pentapeptide-17 is a lipopeptide composed of a pentapeptide sequence conjugated to myristic acid, intended to improve penetration into the skin and…

    Dermatology · Research Phase · Topical

    No lawful pathway
  17. 017

    Palmitoyl Tripeptide-1

    Palmitoyl Tripeptide-1 (also called Pal-GHK) is a synthetic lipopeptide in which the tripeptide glycyl-histidyl-lysine (GHK) is linked to palmitic acid to…

    Dermatology · Research Phase · Topical

    No lawful pathway
  18. 018

    Copper Peptide (Prezatide Copper Acetate)

    Prezatide copper acetate is the copper complex of the tripeptide glycyl-histidyl-lysine (GHK-Cu), a peptide originally isolated from human plasma. In…

    Dermatology · Investigational · Topical

    No lawful pathway
  19. 019

    Melitane (Acetyl Hexapeptide-1)

    Acetyl Hexapeptide-1 (trade name Melitane) is a synthetic hexapeptide cosmetic ingredient designed as a biomimetic of alpha-melanocyte-stimulating hormone…

    Dermatology · Research Phase · Topical

    No lawful pathway

Index · all 264 peptides, A–Z

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Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association checks each clinician’s NPI record but does not employ or directly supervise these clinicians.

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