Peptide Association

Insights

NewsBlog
Start free intake

DisclosurePeptide Association LLC is a for-profit company. We receive compensation from the clinical providers listed on this site. We are not an accrediting body, a licensing board, or a government-affiliated organization. See exactly how we make money.

The compound database

Peptide Database

264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.

FDA-approved
90
FDA-approved
Awaiting FDA
8
Awaiting FDA
No lawful pathway
166
No lawful pathway
1–13 of 13 · AntimicrobialClear filters
  1. 001

    Enfuvirtide (Fuzeon)

    A 36-amino acid synthetic peptide that inhibits HIV-1 entry into CD4+ T-cells by blocking gp41-mediated membrane fusion. Enfuvirtide binds the first heptad…

    Antimicrobial · FDA Approved · Subcutaneous injection (twice daily)

    FDA-approved
  2. 002

    Magainin 2

    Magainin 2 is one of a family of 23-amino acid antimicrobial peptides isolated from the skin of the African clawed frog Xenopus laevis. The magainins are water…

    Antimicrobial · Research Phase · Topical

    No lawful pathway
  3. 003

    Pexiganan (MSI-78)

    Pexiganan is a 22-amino acid synthetic analog of magainin 2. It is a cationic membrane-active peptide with broad-spectrum antibacterial activity, and it was…

    Antimicrobial · Investigational · Topical

    No lawful pathway
  4. 004

    Omiganan

    Omiganan is a synthetic cationic antimicrobial peptide derived from indolicidin, a naturally occurring peptide from bovine neutrophils. It acts by disrupting…

    Antimicrobial · In Clinical Trials · Topical

    No lawful pathway
  5. 005

    Iseganan (IB-367)

    Iseganan is a synthetic analog of protegrin, a naturally occurring antimicrobial peptide found in porcine leukocytes, with broad-spectrum microbicidal activity…

    Antimicrobial · Investigational · Oral rinse

    No lawful pathway
  6. 006

    Defensin HNP-1

    Human neutrophil peptide 1 (HNP-1) is an alpha-defensin, one of three alpha-defensins that human neutrophils contain in large amounts. Defensins are small…

    Antimicrobial · Research Phase · Topical, Intravenous

    No lawful pathway
  7. 007

    Alpha-Defensin 5

    Alpha-defensin 5, also called human defensin 5 or HD-5, is an alpha-defensin secreted by Paneth cells, the specialized epithelia of the small intestinal crypt.…

    Antimicrobial · Research Phase · Oral, Topical

    No lawful pathway
  8. 008

    Lactoferricin

    Lactoferricin is an antimicrobial peptide released by pepsin-mediated cleavage of lactoferrin, an iron-binding glycoprotein found in milk and mucosal…

    Antimicrobial · Investigational · Oral, Topical

    No lawful pathway
  9. 009

    Nisin

    Nisin is a polycyclic antibacterial peptide (lantibiotic) produced by Lactococcus lactis. It acts against Gram-positive bacteria, binding lipid II, the…

    Antimicrobial · Investigational · Topical, Oral

    No lawful pathway
  10. 010

    Gramicidin S

    Gramicidin S is a cyclic decapeptide antibiotic consisting of two identical pentapeptide sequences joined in a ring. It kills bacteria by disrupting cell…

    Antimicrobial · Investigational · Topical

    No lawful pathway
  11. 011

    Polymyxin B

    Polymyxin B is a cyclic lipopeptide antibiotic consisting of a heptapeptide ring and a tripeptide side chain acylated with a fatty acid tail. It binds…

    Antimicrobial · FDA Approved · Intravenous, Intrathecal, Topical

    FDA-approved
  12. 012

    Colistin (Polymyxin E)

    Colistin, also known as polymyxin E, is a cyclic polypeptide antibiotic structurally similar to polymyxin B. It disrupts the Gram-negative outer membrane by…

    Antimicrobial · FDA Approved · Intravenous, Intramuscular, Inhalation

    FDA-approved
  13. 013

    Indolicidin

    Indolicidin is a 13-residue antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils, unusually rich in tryptophan and proline.…

    Antimicrobial · Research Phase · Topical

    No lawful pathway

Index · all 264 peptides, A–Z

Important Medical Disclaimer

The information provided by the Peptide Association is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified, licensed healthcare provider before beginning any peptide therapy, supplement regimen, or making changes to an existing treatment plan.

Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association checks each clinician’s NPI record but does not employ or directly supervise these clinicians.

© 2026 The Peptide Association. All rights reserved. Content on this site is protected under applicable intellectual property laws. The Peptide Association is not a medical practice.