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The compound database

Peptide Database

264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.

FDA-approved
90
FDA-approved
Awaiting FDA
8
Awaiting FDA
No lawful pathway
166
No lawful pathway
1–28 of 28 · HormoneClear filters
  1. 001

    CJC-1295

    A synthetic analog of growth hormone-releasing hormone (GHRH) with a Drug Affinity Complex (DAC) that binds to albumin, extending its half-life from minutes to…

    Hormone · Investigational · Subcutaneous injection

    Awaiting FDA
  2. 002

    Ipamorelin

    A synthetic pentapeptide growth hormone secretagogue that acts on ghrelin/GHS receptors to stimulate GH release. In swine, ipamorelin released GH without…

    Hormone · Investigational · Subcutaneous injection

    Awaiting FDA
  3. 003

    Sermorelin

    A synthetic 29-amino acid analog of GHRH corresponding to the shortest fully functional fragment of the native 44-amino acid hormone. Sermorelin stimulates…

    Hormone · FDA Approved · Subcutaneous injection

    FDA-approved
  4. 004

    Tesamorelin (Egrifta)

    A synthetic GHRH analog consisting of the full 44-amino acid sequence of human GHRH with a trans-3-hexenoic acid modification at the N-terminus to improve…

    Hormone · FDA Approved · Subcutaneous injection (daily)

    FDA-approved
  5. 005

    PT-141 (Bremelanotide / Vyleesi)

    A synthetic cyclic heptapeptide melanocortin receptor agonist structurally related to melanotan II. Unlike PDE5 inhibitors that act peripherally on vascular…

    Hormone · FDA Approved · Subcutaneous injection (as needed)

    FDA-approved
  6. 006

    Kisspeptin

    A family of neuropeptides encoded by the KISS1 gene that act as key upstream regulators of the hypothalamic-pituitary-gonadal (HPG) axis. Kisspeptin activates…

    Hormone · In Clinical Trials · Intravenous, Subcutaneous injection

    No lawful pathway
  7. 007

    Oxytocin

    A nine-amino acid cyclic neuropeptide produced mainly in the hypothalamus and released from the posterior pituitary in response to stimuli such as suckling…

    Hormone · FDA Approved · Intravenous, Intramuscular injection, Intranasal

    FDA-approved
  8. 008

    GHRP-2

    A synthetic hexapeptide growth hormone secretagogue (also called pralmorelin) that acts on the ghrelin receptor (GHS-R1a) in the hypothalamus and pituitary to…

    Hormone · Investigational · Subcutaneous injection, Intravenous

    No lawful pathway
  9. 009

    GHRP-6

    A synthetic hexapeptide growth hormone secretagogue that stimulates GH release via the ghrelin receptor (GHS-R1a). In healthy men, most of its GH-releasing…

    Hormone · Investigational · Subcutaneous injection, Intravenous

    No lawful pathway
  10. 010

    Hexarelin

    A synthetic hexapeptide growth hormone secretagogue that causes profound GH release in humans after oral, intranasal, intravenous or subcutaneous…

    Hormone · Investigational · Subcutaneous injection, Intravenous

    No lawful pathway
  11. 011

    MK-677 (Ibutamoren)

    An orally active, non-peptide growth hormone secretagogue that mimics ghrelin at the GHS-R1a receptor. In healthy older adults, once-daily oral MK-677…

    Hormone · In Clinical Trials · Oral

    No lawful pathway
  12. 012

    Macimorelin (Macrilen)

    An orally active ghrelin mimetic and growth hormone secretagogue developed as a diagnostic agent for adult growth hormone deficiency (AGHD). Macimorelin…

    Hormone · FDA Approved · Oral

    FDA-approved
  13. 013

    Cosyntropin (Cortrosyn)

    A synthetic peptide consisting of the first 24 amino acids of the 39-amino acid adrenocorticotropic hormone (ACTH). Cosyntropin reproduces the…

    Hormone · FDA Approved · Intravenous, Intramuscular injection

    FDA-approved
  14. 014

    Gonadorelin (GnRH)

    A synthetic decapeptide identical to endogenous gonadotropin-releasing hormone. A pulsatile pattern of GnRH is required for pituitary stimulation and release…

    Hormone · FDA Approved · Intravenous, Subcutaneous injection

    FDA-approved
  15. 015

    Capromorelin (Entyce)

    Capromorelin is a ghrelin receptor agonist (growth hormone secretagogue) that mimics ghrelin by binding the GHS-R1a receptor, which stimulates appetite and…

    Hormone · Investigational · Oral

    No lawful pathway
  16. 016

    Anamorelin (Adlumiz)

    Anamorelin is an orally active ghrelin receptor agonist that acts at the growth hormone secretagogue receptor (GHS-R1a) to stimulate appetite, food intake…

    Hormone · In Clinical Trials · Oral

    No lawful pathway
  17. 017

    Relamorelin

    Relamorelin (RM-131) is a synthetic pentapeptide ghrelin receptor agonist that activates the GHS-1a receptor with about sixfold greater potency than native…

    Hormone · Investigational · Subcutaneous injection

    No lawful pathway
  18. 018

    Mod GRF 1-29 (CJC-1295 no DAC)

    Modified GRF 1-29 is a synthetic analogue of the first 29 amino acids of growth hormone-releasing hormone (GHRH) with four amino acid substitutions, the same…

    Hormone · Research Phase · Subcutaneous injection

    No lawful pathway
  19. 019

    Tabimorelin

    Tabimorelin (NN703) is an orally active synthetic growth hormone secretagogue that acts as an agonist at the ghrelin receptor (GHS-R1a) to stimulate growth…

    Hormone · Investigational · Oral

    No lawful pathway
  20. 020

    Somatropin (Genotropin)

    Somatropin is recombinant human growth hormone (rhGH) consisting of 191 amino acids identical in sequence to endogenous pituitary growth hormone. It binds to…

    Hormone · FDA Approved · Subcutaneous injection

    FDA-approved
  21. 021

    Somapacitan (Sogroya)

    Somapacitan is a long-acting growth hormone derivative engineered to bind reversibly to albumin, which extends its half-life to allow once-weekly subcutaneous…

    Hormone · FDA Approved · Subcutaneous injection

    FDA-approved
  22. 022

    Lonapegsomatropin (Skytrofa)

    Lonapegsomatropin is a long-acting prodrug of somatropin in which growth hormone is transiently linked to a polyethylene glycol carrier through a cleavable…

    Hormone · FDA Approved · Subcutaneous injection

    FDA-approved
  23. 023

    Pegvisomant (Somavert)

    Pegvisomant is a PEGylated growth hormone receptor antagonist engineered from human growth hormone with amino acid substitutions that confer antagonist…

    Hormone · FDA Approved · Subcutaneous injection

    FDA-approved
  24. 024

    Mecasermin (Increlex)

    Mecasermin is recombinant human insulin-like growth factor 1 (IGF-1) consisting of 70 amino acids identical to the endogenous peptide hormone. It binds to…

    Hormone · FDA Approved · Subcutaneous injection

    FDA-approved
  25. 025

    GHRH (Sermorelin 1-44)

    Growth hormone releasing hormone (GHRH) is a 44-amino acid hypothalamic peptide that stimulates growth hormone secretion from the anterior pituitary by binding…

    Hormone · FDA Approved · Subcutaneous injection

    FDA-approved
  26. 026

    Ghrelin (Native)

    Ghrelin is a naturally occurring 28-amino acid peptide hormone with an n-octanoyl modification at serine-3 that is essential for its growth hormone releasing…

    Hormone · Investigational · Intravenous

    No lawful pathway
  27. 027

    Obestatin

    Obestatin is a 23-amino acid peptide derived from the same precursor as ghrelin, preproghrelin. It was initially reported to oppose ghrelin by suppressing food…

    Hormone · Research Phase · Subcutaneous injection, Intravenous

    No lawful pathway
  28. 028

    GHRP-1

    Growth Hormone Releasing Peptide-1 is a synthetic heptapeptide (seven amino acids) belonging to the growth hormone secretagogue family. It acts on the growth…

    Hormone · Investigational · Subcutaneous injection, Intravenous

    No lawful pathway

Index · all 264 peptides, A–Z

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