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Vialox (Pentapeptide-3)
Overview
Vialox is a synthetic pentapeptide designed to modulate neuromuscular signaling by interfering with acetylcholine receptor activation. The exact sequence is proprietary, but the peptide is marketed as a topical agent to reduce muscle contraction intensity in areas prone to dynamic wrinkles.
Mechanism of Action
It is positioned alongside other neuromodulating peptides as a non-invasive alternative to botulinum toxin.
Research Summary & Key Findings
Manufacturer-provided data suggest that pentapeptide-3 can reduce muscle contraction frequency in ex vivo tissue models. Small cosmetic trials have reported subjective improvements in expression line severity after 28 days, though methodological details and independent replication are lacking. No studies in indexed dermatology or pharmacology journals have validated clinical efficacy or safety profiles.
Clinical Status
Vialox (Pentapeptide-3) is in the investigational stage. While preclinical and early-phase data exist, it has not received regulatory approval for clinical use in the United States.
Administration Routes
References
Primary literature
- PubMed: "Vialox"
Peer-reviewed literature indexed by the National Library of Medicine.
- ClinicalTrials.gov: "Vialox"
Registered interventional and observational studies, including status and phase.
- PubChem: "Vialox"
Chemical structure, molecular properties, and bioactivity data.
Study-level citations for this compound are being verified against the primary sources before publication. The database queries above return the current indexed literature in the meantime.
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View detailsNo lawful pathway today
Vialox (Pentapeptide-3) is not FDA-approved and does not currently have a lawful prescription or compounding pathway in the United States, so there is nothing for us to sell you here and no consultation to book. That can change: eight peptides moved back to a lawful pathway in February 2026.
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One email, only if this compound's regulatory standing actually moves. Not a newsletter, not a sales sequence.
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List Your PracticeDisclaimer: This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide therapy. The Peptide Association does not endorse or recommend any specific treatment protocol. See our editorial policy for how this content is produced and reviewed.