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Peptide Database

265 therapeutic peptides with research summaries, clinical findings, and regulatory status.

Showing 1–36 of 265
RecoveryResearch Phase

BPC-157

A synthetic gastric pentadecapeptide derived from a protein found in human gastric juice. BPC-157 promotes angiogenesis and the expression of growth…

Subcutaneous injection, Oral
RecoveryIn Clinical Trials

TB-500 (Thymosin Beta-4)

Thymosin Beta-4 is a 43-amino acid actin-sequestering protein involved in cell migration, differentiation, and tissue repair. It promotes wound…

Subcutaneous injection
RecoveryResearch Phase

GHK-Cu

A naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) found in human plasma, saliva, and urine. GHK-Cu activates tissue…

Topical, Subcutaneous injection
RecoveryResearch Phase

DSIP (Delta Sleep-Inducing Peptide)

A naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) originally isolated from cerebral venous blood of rabbits during induced…

Subcutaneous injection, Intravenous, Intranasal
RecoveryFDA Approved

Pentosan Polysulfate (Elmiron)

A semi-synthetic sulfated polysaccharide derived from beechwood hemicellulose with structural similarities to glycosaminoglycans. Pentosan…

Oral
MetabolicFDA Approved

Semaglutide (Ozempic/Wegovy)

A glucagon-like peptide-1 receptor agonist (GLP-1 RA) with 94% amino acid homology to native GLP-1. Semaglutide enhances glucose-dependent insulin…

Subcutaneous injection (weekly), Oral (daily - Rybelsus)
MetabolicFDA Approved

Tirzepatide (Mounjaro/Zepbound)

A first-in-class dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist. Tirzepatide activates both incretin pathways…

Subcutaneous injection (weekly)
MetabolicIn Clinical Trials

Retatrutide

An investigational triple hormone receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously. The glucagon receptor component adds…

Subcutaneous injection (weekly)
MetabolicInvestigational

AOD-9604

A modified 16-amino acid fragment (amino acids 176-191) of the C-terminus of human growth hormone with an added tyrosine at the N-terminus. AOD-9604…

Subcutaneous injection, Oral
MetabolicFDA Approved

Liraglutide (Saxenda/Victoza)

A GLP-1 receptor agonist with 97% homology to native GLP-1, modified with a fatty acid side chain (C-16 palmitoyl) enabling albumin binding and a…

Subcutaneous injection (daily)
MetabolicFDA Approved

Exenatide (Byetta/Bydureon)

A synthetic version of exendin-4, a 39-amino acid peptide originally isolated from the saliva of the Gila monster lizard (Heloderma suspectum).…

Subcutaneous injection (twice daily or weekly extended-release)
MetabolicFDA Approved

Glucagon

A 29-amino acid peptide hormone produced by alpha cells of the pancreatic islets of Langerhans. Glucagon acts primarily on hepatocytes via the…

Subcutaneous injection, Intramuscular injection, Intranasal
MetabolicFDA Approved

Pramlintide (Symlin)

A synthetic analog of amylin (islet amyloid polypeptide), a 37-amino acid peptide hormone co-secreted with insulin from pancreatic beta cells.…

Subcutaneous injection (before meals)
MetabolicFDA Approved

Dulaglutide (Trulicity)

A long-acting GLP-1 receptor agonist consisting of a GLP-1 analog covalently linked to a modified human IgG4 Fc fragment via a peptide linker. This…

Subcutaneous injection (weekly)
MetabolicFDA Approved

Lixisenatide (Adlyxin)

A selective GLP-1 receptor agonist derived from exendin-4 with a modified C-terminal tail containing six lysine residues. Lixisenatide has a…

Subcutaneous injection (daily)
MetabolicFDA Approved

Setmelanotide (Imcivree)

A cyclic peptide melanocortin-4 receptor (MC4R) agonist designed to restore MC4R signaling in patients with obesity caused by genetic deficiencies in…

Subcutaneous injection (daily)
HormoneIn Clinical Trials

CJC-1295

A synthetic analog of growth hormone-releasing hormone (GHRH) with a Drug Affinity Complex (DAC) that binds to albumin, extending its half-life from…

Subcutaneous injection
HormoneIn Clinical Trials

Ipamorelin

A highly selective growth hormone secretagogue that acts on ghrelin/GHS receptors in the pituitary gland to stimulate GH release. Unlike other GH…

Subcutaneous injection
HormoneFDA Approved

Sermorelin

A synthetic 29-amino acid analog of GHRH representing the shortest fully functional fragment of the native 44-amino acid hormone. Sermorelin…

Subcutaneous injection
HormoneFDA Approved

Tesamorelin (Egrifta)

A synthetic GHRH analog consisting of the 44-amino acid sequence of human GHRH with a trans-3-hexenoic acid modification at the N-terminus to improve…

Subcutaneous injection (daily)
HormoneFDA Approved

PT-141 (Bremelanotide / Vyleesi)

A synthetic cyclic heptapeptide melanocortin receptor agonist that activates MC3R and MC4R in the central nervous system. Unlike PDE5 inhibitors that…

Subcutaneous injection (as needed)
HormoneIn Clinical Trials

Kisspeptin

A neuropeptide encoded by the KISS1 gene that serves as the master upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis. Kisspeptin…

Intravenous, Subcutaneous injection
HormoneFDA Approved

Oxytocin

A nine-amino acid cyclic neuropeptide produced in the hypothalamus and released from the posterior pituitary. Oxytocin mediates uterine contractions…

Intravenous, Intramuscular injection, Intranasal
HormoneInvestigational

GHRP-2

A synthetic hexapeptide growth hormone secretagogue that acts on the ghrelin receptor (GHS-R1a) in the hypothalamus and pituitary to stimulate growth…

Subcutaneous injection, Intravenous
HormoneInvestigational

GHRP-6

A synthetic hexapeptide growth hormone secretagogue that stimulates the anterior pituitary via GHS-R1a receptor activation. GHRP-6 produces…

Subcutaneous injection, Intravenous
HormoneInvestigational

Hexarelin

A synthetic hexapeptide growth hormone secretagogue with the highest GH-releasing potency among GHRPs. Hexarelin binds both GHS-R1a and CD36…

Subcutaneous injection, Intravenous
HormoneIn Clinical Trials

MK-677 (Ibutamoren)

An orally bioavailable, non-peptide growth hormone secretagogue that mimics the action of ghrelin at the GHS-R1a receptor. MK-677 stimulates…

Oral
HormoneFDA Approved

Macimorelin (Macrilen)

An orally bioavailable growth hormone secretagogue approved as a diagnostic agent for adult growth hormone deficiency (AGHD). Macimorelin stimulates…

Oral
HormoneFDA Approved

Cosyntropin (Cortrosyn)

A synthetic peptide consisting of the first 24 amino acids of the 39-amino acid adrenocorticotropic hormone (ACTH). Cosyntropin retains full…

Intravenous, Intramuscular injection
HormoneFDA Approved

Gonadorelin (GnRH)

A synthetic decapeptide identical to endogenous gonadotropin-releasing hormone. Gonadorelin stimulates the release of luteinizing hormone (LH) and…

Intravenous, Subcutaneous injection
ReproductiveFDA Approved

Leuprolide (Lupron)

A synthetic nonapeptide GnRH agonist approximately 15-fold more potent than native GnRH. After an initial stimulatory phase (flare effect) lasting…

Subcutaneous injection, Intramuscular injection (depot)
ReproductiveFDA Approved

Goserelin (Zoladex)

A synthetic decapeptide GnRH agonist administered as a biodegradable subcutaneous implant that provides sustained drug release over 1 or 3 months.…

Subcutaneous implant
ReproductiveFDA Approved

Cetrorelix (Cetrotide)

A synthetic decapeptide GnRH antagonist that competitively blocks pituitary GnRH receptors, producing immediate and dose-dependent suppression of LH…

Subcutaneous injection
ReproductiveFDA Approved

Ganirelix

A synthetic decapeptide GnRH antagonist that competitively and reversibly blocks GnRH receptors on pituitary gonadotroph cells. Ganirelix rapidly…

Subcutaneous injection
ReproductiveIn Clinical Trials

Carbetocin

A long-acting synthetic analog of oxytocin with a modified disulfide bridge that confers resistance to enzymatic degradation. Carbetocin has a…

Intravenous, Intramuscular injection
ReproductiveInvestigational

Atosiban

A competitive oxytocin/vasopressin V1a receptor antagonist used as a tocolytic agent to delay preterm labor. Atosiban blocks oxytocin-mediated…

Intravenous

All 265 peptides

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Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association reviews licensure but does not employ or directly supervise these clinicians.

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