Longevity · Research Phase
Gerontin (Pineal Gland Extract)
No lawful US pathway
01 · Overview
Gerontin is a name applied to peptide fractions derived from pineal gland extracts in Russian gerontology research. No publications indexed in PubMed under this name were identified, and the preparations are not standardized or chemically characterized by modern analytical methods.
The most studied comparable Russian pineal peptide preparation is epithalamin, which has been examined in animal models of aging (PMID 9701766). Any biological rationale rests on the pineal gland role in melatonin synthesis and circadian coordination.
02 · Research summary & key findings
Published evidence for Russian pineal peptide preparations is confined to animal work: treatment with epithalamin increased mean lifespan by 11 to 31 percent in female fruit flies, two mouse strains and rats, decreased mortality rate, and was reported to increase melatonin secretion and inhibit free radical processes in rats and flies (PMID 9701766). No peer-reviewed human trials, and no studies published under the name gerontin, were identified. The absence of chemical characterization, regulatory approval and controlled human data leaves its clinical utility unestablished.
03 · Regulatory status
Gerontin (Pineal Gland Extract) is in the research phase with limited clinical data in humans. Current evidence is primarily derived from preclinical (animal or in vitro) studies.
No lawful pathway today
Gerontin (Pineal Gland Extract) is not FDA-approved and does not currently have a lawful prescription or compounding pathway in the United States, so we do not sell it and will not book a consultation for it. That can change: in 2026 FDA began reviewing several peptides for compounding. If you are working on the goal it is studied for, a licensed clinician can tell you what is lawfully available, which may be something else.
See the 3 FDA-approved compounds in Longevity
Tell me if the status changes
One email, only if this compound's regulatory standing actually moves. Not a newsletter, not a sales sequence.
Looking for a lawful, clinician-prescribed option for longevity and healthy ageing?
Gerontin (Pineal Gland Extract) is a research compound, is not FDA-approved, and has no lawful US compounding pathway, so we do not offer it and no clinician we work with will prescribe it. Products sold online as “research chemicals” are not made or tested to the standards required of medicines. If you are working on longevity and healthy ageing, a licensed clinician can tell you at a free consultation whether an FDA-approved or lawfully compounded treatment fits you, or whether nothing does.
Explore lawful options (free intake)About 3 minutes. If a protocol is prescribed through our provider, we earn 10% of the sale. See the receipts.
04 · Administration routes
- Subcutaneous injection
References
- [1]Pineal peptide preparation epithalamin increases the lifespan of fruit flies, mice and rats Mech Ageing Dev, 1998. PMID 9701766
Primary literature
- PubMed: "Gerontin"
Peer-reviewed literature indexed by the National Library of Medicine.
- ClinicalTrials.gov: "Gerontin"
Registered interventional and observational studies, including status and phase.
- PubChem: "Gerontin"
Chemical structure, molecular properties, and bioactivity data.
Related peptides in Longevity
Disclaimer: This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide therapy. The Peptide Association does not endorse or recommend any specific treatment protocol. See our editorial policy for how this content is produced and reviewed. Clinicians: join the network.