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GHRP-2
Overview
A synthetic hexapeptide growth hormone secretagogue that acts on the ghrelin receptor (GHS-R1a) in the hypothalamus and pituitary to stimulate growth hormone release. GHRP-2 is one of the most potent GH-releasing peptides, producing robust GH pulses while also increasing ACTH, cortisol, and prolactin to a modest degree.
Mechanism of Action
It amplifies the natural GH axis and works synergistically with GHRH analogs.
Research Summary & Key Findings
Clinical studies demonstrated dose-dependent GH release with peak levels at 15-30 minutes post-administration. More potent than GHRP-6 with less appetite stimulation. Used clinically in Japan for GH stimulation testing. Research shows sustained IGF-1 elevation and improved body composition parameters.
Clinical Status
GHRP-2 is in the investigational stage. While preclinical and early-phase data exist, it has not received regulatory approval for clinical use in the United States.
Administration Routes
References
Primary literature
- PubMed: "GHRP-2"
Peer-reviewed literature indexed by the National Library of Medicine.
- ClinicalTrials.gov: "GHRP-2"
Registered interventional and observational studies, including status and phase.
- PubChem: "GHRP-2"
Chemical structure, molecular properties, and bioactivity data.
Study-level citations for this compound are being verified against the primary sources before publication. The database queries above return the current indexed literature in the meantime.
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CJC-1295
In Clinical TrialsA synthetic analog of growth hormone-releasing hormone (GHRH) with a Drug Affinity Complex (DAC) that binds to albumin, ...
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In Clinical TrialsA highly selective growth hormone secretagogue that acts on ghrelin/GHS receptors in the pituitary gland to stimulate GH...
View detailsSermorelin
FDA ApprovedA synthetic 29-amino acid analog of GHRH representing the shortest fully functional fragment of the native 44-amino acid...
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FDA ApprovedA synthetic GHRH analog consisting of the 44-amino acid sequence of human GHRH with a trans-3-hexenoic acid modification...
View detailsNo lawful pathway today
GHRP-2 is not FDA-approved and does not currently have a lawful prescription or compounding pathway in the United States, so there is nothing for us to sell you here and no consultation to book. That can change: eight peptides moved back to a lawful pathway in February 2026.
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