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Imuthiol (Diethyldithiocarbamate)
Overview
Imuthiol is the sodium salt of diethyldithiocarbamate, a small molecule rather than a peptide, historically explored for immune modulation and antiviral properties. It is thought to alter cytokine profiles and scavenge reactive oxygen species.
Mechanism of Action
Therapeutic interest has focused on HIV infection and other states of immune dysregulation.
Research Summary & Key Findings
Early clinical trials in the late 1980s and early 1990s investigated imuthiol in HIV-positive patients, with some studies reporting transient increases in CD4 counts but no durable virologic or clinical benefit. Subsequent development was discontinued due to lack of efficacy in later-stage trials.
Clinical Status
Imuthiol (Diethyldithiocarbamate) is in the investigational stage. While preclinical and early-phase data exist, it has not received regulatory approval for clinical use in the United States.
Administration Routes
References
Primary literature
- PubMed: "Imuthiol"
Peer-reviewed literature indexed by the National Library of Medicine.
- ClinicalTrials.gov: "Imuthiol"
Registered interventional and observational studies, including status and phase.
- PubChem: "Imuthiol"
Chemical structure, molecular properties, and bioactivity data.
Study-level citations for this compound are being verified against the primary sources before publication. The database queries above return the current indexed literature in the meantime.
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View detailsNo lawful pathway today
Imuthiol (Diethyldithiocarbamate) is not FDA-approved and does not currently have a lawful prescription or compounding pathway in the United States, so there is nothing for us to sell you here and no consultation to book. That can change: eight peptides moved back to a lawful pathway in February 2026.
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List Your PracticeDisclaimer: This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide therapy. The Peptide Association does not endorse or recommend any specific treatment protocol. See our editorial policy for how this content is produced and reviewed.