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The compound database

Peptide Database

264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.

FDA-approved
90
FDA-approved
Awaiting FDA
8
Awaiting FDA
No lawful pathway
166
No lawful pathway
1–19 of 19 · CognitiveClear filters
  1. 001

    Semax

    A synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) that combines the ACTH(4-7) fragment with a stabilizing Pro-Gly-Pro tail and is described as an analog…

    Cognitive · Investigational · Intranasal

    Awaiting FDA
  2. 002

    Selank

    A synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) built from the endogenous tetrapeptide tuftsin with an added Pro-Gly-Pro sequence for stability. In…

    Cognitive · Investigational · Intranasal

    Awaiting FDA
  3. 003

    Cerebrolysin

    A porcine brain-derived preparation of low-molecular-weight peptides and amino acids with proposed neurotrophic and neuroprotective properties. In transgenic…

    Cognitive · In Clinical Trials · Intravenous, Intramuscular injection

    No lawful pathway
  4. 004

    P21 (Peptide)

    A small synthetic peptide (P021) derived from the most active region of ciliary neurotrophic factor (CNTF), with an adamantylated glycine added to improve…

    Cognitive · Research Phase · Subcutaneous injection, Intranasal

    No lawful pathway
  5. 005

    Dihexa

    Dihexa (N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, also called PNB-0408) is a small synthetic angiotensin IV analogue rather than a true hexapeptide. Its…

    Cognitive · Research Phase · Oral, Subcutaneous injection

    No lawful pathway
  6. 006

    NAP (Davunetide)

    NAP, also known as davunetide, is an eight-amino acid peptide derived from activity-dependent neuroprotective protein (ADNP). In preclinical studies it…

    Cognitive · Investigational · Intranasal

    No lawful pathway
  7. 007

    Nemifitide

    Nemifitide (formerly INN 00835) is a synthetic pentapeptide analogue of melanocyte-inhibiting factor (MIF), not of alpha-MSH, developed as a fast-acting…

    Cognitive · Investigational · Intravenous

    No lawful pathway
  8. 008

    Intranasal Insulin

    Intranasal insulin involves the administration of regular human insulin via nasal spray to target central nervous system insulin receptors while minimizing…

    Cognitive · In Clinical Trials · Intranasal

    No lawful pathway
  9. 009

    Spadin

    Spadin is a 17-amino acid peptide derived from the propeptide released during maturation of sortilin, also known as neurotensin receptor 3. It blocks the…

    Cognitive · Research Phase · Intravenous, Intranasal

    No lawful pathway
  10. 010

    Cortexin

    Cortexin is a complex mixture of low-molecular-weight polypeptides extracted from animal cerebral cortex and used mainly in Russia and neighboring countries…

    Cognitive · In Clinical Trials · Intramuscular injection

    No lawful pathway
  11. 011

    Pinealon

    Pinealon is a synthetic tripeptide (Glu-Asp-Arg, also called EDR) developed as part of the Khavinson peptide bioregulator series, designed to mimic endogenous…

    Cognitive · Investigational · Subcutaneous injection, Oral

    No lawful pathway
  12. 012

    N-acetyl Semax Amidate

    N-acetyl Semax Amidate is a modified form of Semax, a heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) combining the ACTH 4-7 sequence with a C-terminal Pro-Gly-Pro…

    Cognitive · Research Phase · Intranasal, Subcutaneous injection

    No lawful pathway
  13. 013

    N-acetyl Selank Amidate

    N-acetyl Selank Amidate is a modified form of Selank, a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) built on the immunomodulatory peptide tuftsin with…

    Cognitive · Research Phase · Intranasal

    No lawful pathway
  14. 014

    Bromantane-adjacent Peptides

    Bromantane-adjacent peptides refer to a theoretical class of compounds that might share functional goals with bromantane, a synthetic adamantane derivative…

    Cognitive · Research Phase · Not established

    No lawful pathway
  15. 015

    ACTH (4-10) Analogs

    ACTH (4-10) analogs are synthetic peptides derived from the 4 to 10 amino acid sequence of adrenocorticotropic hormone, a fragment that retains behavioral…

    Cognitive · Investigational · Intranasal, Subcutaneous injection

    No lawful pathway
  16. 016

    Orexin A

    Orexin A (hypocretin-1) is a 33-amino acid neuropeptide produced by neurons in the lateral and posterior hypothalamus, first identified as a regulator of…

    Cognitive · Investigational · Intracerebroventricular

    No lawful pathway
  17. 017

    Orexin B

    Orexin B (hypocretin-2) is a 28-amino acid neuropeptide derived from the same precursor as orexin A and produced in hypothalamic neurons; central…

    Cognitive · Research Phase · Intracerebroventricular

    No lawful pathway
  18. 018

    Neurotensin

    Neurotensin is a 13-amino acid neuropeptide found in the central nervous system and gastrointestinal tract, where it modulates dopamine neurotransmission…

    Cognitive · Investigational · Intravenous, Intracerebroventricular

    No lawful pathway
  19. 019

    Galanin

    Galanin is a 29 or 30 amino acid neuropeptide widely expressed in the brain, acting through three G protein-coupled receptor subtypes, GalR1, GalR2, and GalR3…

    Cognitive · Investigational · Intravenous

    No lawful pathway

Index · all 264 peptides, A–Z

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