Peptide Association LLC is a for-profit company. We receive compensation from the clinical providers listed on this site. We are not an accrediting body, a licensing board, or a government-affiliated organization. See exactly how we make money.

Peptide Database

265 therapeutic peptides with research summaries, clinical findings, and regulatory status.

Showing 1–15 of 15 in GastrointestinalClear filters
GastrointestinalFDA Approved

Octreotide (Sandostatin)

A synthetic octapeptide analog of somatostatin with a substantially longer half-life (90 minutes IV, 6 hours subcutaneous vs. 2 minutes for native…

Subcutaneous injection, Intramuscular injection (LAR), Intravenous
GastrointestinalFDA Approved

Lanreotide (Somatuline Depot)

A synthetic octapeptide analog of somatostatin with high affinity for SSTR2 and moderate affinity for SSTR5 receptors. Lanreotide is formulated as a…

Deep subcutaneous injection (monthly)
GastrointestinalFDA Approved

Pasireotide (Signifor)

A multireceptor-targeted somatostatin analog with high binding affinity for SSTR1, SSTR2, SSTR3, and SSTR5, particularly notable for its 40-fold…

Subcutaneous injection (twice daily), Intramuscular injection (monthly LAR)
GastrointestinalFDA Approved

Plecanatide (Trulance)

A synthetic 16-amino acid peptide structurally related to uroguanylin, an endogenous intestinal peptide that regulates fluid and electrolyte…

Oral
GastrointestinalFDA Approved

Linaclotide (Linzess)

A synthetic 14-amino acid peptide structurally related to the heat-stable enterotoxin of Escherichia coli and the endogenous peptide guanylin.…

Oral
GastrointestinalFDA Approved

Secretin

A 27-amino acid peptide hormone produced by S-cells of the duodenal and jejunal mucosa in response to acidic chyme entering the small intestine.…

Intravenous
GastrointestinalIn Clinical Trials

Larazotide

A synthetic octapeptide derived from Vibrio cholerae zonula occludens toxin that acts as a tight junction regulator. Larazotide acetate modulates…

Oral
GastrointestinalResearch Phase

Glucagon Receptor Antagonist Peptides

Glucagon receptor antagonist peptides are a class of molecules designed to block the glucagon receptor and prevent glucagon-mediated hepatic glucose…

Subcutaneous injection
GastrointestinalResearch Phase

Motilin

Motilin is a 22-amino acid endogenous peptide hormone secreted by enteroendocrine cells in the duodenum and jejunum. It binds to motilin receptors on…

Intravenous
GastrointestinalFDA Approved

Cholecystokinin (CCK)

Cholecystokinin is an endogenous peptide hormone existing in multiple forms, most commonly as CCK-8 and CCK-33, secreted by I-cells in the duodenum…

Intravenous
GastrointestinalResearch Phase

Gastrin

Gastrin is an endogenous peptide hormone secreted by G-cells in the gastric antrum and duodenum, existing primarily as gastrin-17 and gastrin-34. It…

Subcutaneous injection, Intravenous
GastrointestinalIn Clinical Trials

Peptide YY (PYY 3-36)

Peptide YY 3-36 is a 34-amino acid endogenous peptide hormone secreted by L-cells in the distal small intestine and colon in response to nutrient…

Intravenous, Intranasal
GastrointestinalIn Clinical Trials

Ghrelin Receptor Antagonists

Ghrelin receptor antagonists are a class of peptides and peptidomimetics designed to block the growth hormone secretagogue receptor (GHSR), also…

Subcutaneous injection, Oral
GastrointestinalResearch Phase

Guanylin

Guanylin is a 15-amino acid endogenous peptide hormone that activates guanylate cyclase-C (GC-C) receptors on intestinal epithelial cells. Upon…

Endogenous peptide
GastrointestinalIn Clinical Trials

Uroguanylin (Dolcanatide)

Uroguanylin is a 16-amino acid endogenous peptide structurally related to guanylin that also activates guanylate cyclase-C receptors in the…

Oral

All 265 peptides

Complete index, every profile, one click away.

Important Medical Disclaimer

The information provided by the Peptide Association is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified, licensed healthcare provider before beginning any peptide therapy, supplement regimen, or making changes to an existing treatment plan.

Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association reviews licensure but does not employ or directly supervise these clinicians.

© 2026 The Peptide Association. All rights reserved. Content on this site is protected under applicable intellectual property laws. HIPAA-compliant infrastructure. The Peptide Association is not a medical practice.