Peptide Association

Insights

NewsBlog
Start free intake

DisclosurePeptide Association LLC is a for-profit company. We receive compensation from the clinical providers listed on this site. We are not an accrediting body, a licensing board, or a government-affiliated organization. See exactly how we make money.

The compound database

Peptide Database

264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.

FDA-approved
90
FDA-approved
Awaiting FDA
8
Awaiting FDA
No lawful pathway
166
No lawful pathway
1–15 of 15 · GastrointestinalClear filters
  1. 001

    Octreotide (Sandostatin)

    A synthetic eight-amino acid analog of somatostatin with a much longer duration of action than native somatostatin, whose very short half-life requires…

    Gastrointestinal · FDA Approved · Subcutaneous injection, Intramuscular injection (LAR), Intravenous

    FDA-approved
  2. 002

    Lanreotide (Somatuline Depot)

    A synthetic octapeptide analog of somatostatin with high affinity for SSTR2 and lower affinity for SSTR5. The long-acting formulation (Autogel, sold in the US…

    Gastrointestinal · FDA Approved · Deep subcutaneous injection (monthly)

    FDA-approved
  3. 003

    Pasireotide (Signifor)

    A multireceptor-targeted somatostatin analog with affinity for SSTR1, SSTR2, SSTR3 and SSTR5, including high affinity for SSTR5. Corticotroph adenomas in…

    Gastrointestinal · FDA Approved · Subcutaneous injection (twice daily), Intramuscular injection (monthly LAR)

    FDA-approved
  4. 004

    Plecanatide (Trulance)

    A synthetic 16-amino acid analog of uroguanylin, an endogenous intestinal peptide that regulates fluid and electrolyte balance in the GI tract. Plecanatide…

    Gastrointestinal · FDA Approved · Oral

    FDA-approved
  5. 005

    Linaclotide (Linzess)

    A synthetic 14-amino acid peptide structurally related to the heat-stable enterotoxin of Escherichia coli and the endogenous peptide guanylin. Linaclotide is a…

    Gastrointestinal · FDA Approved · Oral

    FDA-approved
  6. 006

    Secretin

    A 27-amino acid peptide hormone produced by S-cells of the duodenal and jejunal mucosa in response to acid entering the small intestine. Secretin stimulates…

    Gastrointestinal · FDA Approved · Intravenous

    FDA-approved
  7. 007

    Larazotide

    A synthetic octapeptide tight junction regulator derived from a Vibrio cholerae toxin, described as a zonulin antagonist. In laboratory studies larazotide…

    Gastrointestinal · Investigational · Oral

    No lawful pathway
  8. 008

    Glucagon Receptor Antagonist Peptides

    Glucagon receptor antagonist peptides are molecules designed to block the glucagon receptor and prevent glucagon-driven hepatic glucose output. Most are…

    Gastrointestinal · Research Phase · Subcutaneous injection

    No lawful pathway
  9. 009

    Motilin

    Motilin is a 22-amino acid peptide hormone released from endocrine cells of the duodenal mucosa at roughly 100-minute intervals during fasting, and it is a key…

    Gastrointestinal · Investigational · Intravenous

    No lawful pathway
  10. 010

    Cholecystokinin (CCK)

    Cholecystokinin (CCK) is a family of peptide hormones and neurotransmitters derived from proCCK; the main circulating forms are CCK-58, CCK-33, CCK-22, and…

    Gastrointestinal · FDA Approved · Intravenous

    FDA-approved
  11. 011

    Gastrin

    Gastrin is a peptide hormone made mainly in antroduodenal G-cells, with gastrin-34 and gastrin-17 as the major forms in tissue and plasma. It acts on the CCK2…

    Gastrointestinal · Investigational · Subcutaneous injection, Intravenous

    No lawful pathway
  12. 012

    Peptide YY (PYY 3-36)

    Peptide YY 3-36 is a 34-amino acid fragment of the 36-amino acid gut hormone peptide YY, which is released from intestinal L-cells after meals in proportion to…

    Gastrointestinal · In Clinical Trials · Intravenous, Intranasal

    No lawful pathway
  13. 013

    Ghrelin Receptor Antagonists

    Ghrelin receptor antagonists are peptides, peptidomimetics, and small molecules designed to block the growth hormone secretagogue receptor (GHSR), also known…

    Gastrointestinal · In Clinical Trials · Subcutaneous injection, Oral

    No lawful pathway
  14. 014

    Guanylin

    Guanylin is a 15-amino acid peptide hormone that activates guanylate cyclase-C (GC-C) receptors on intestinal epithelial cells. Binding raises intracellular…

    Gastrointestinal · Research Phase · Endogenous peptide

    No lawful pathway
  15. 015

    Uroguanylin (Dolcanatide)

    Uroguanylin is a 16-amino acid peptide related to guanylin that activates guanylate cyclase-C (GC-C) receptors in the intestinal epithelium. Like guanylin, it…

    Gastrointestinal · Investigational · Oral

    No lawful pathway

Index · all 264 peptides, A–Z

Important Medical Disclaimer

The information provided by the Peptide Association is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified, licensed healthcare provider before beginning any peptide therapy, supplement regimen, or making changes to an existing treatment plan.

Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association checks each clinician’s NPI record but does not employ or directly supervise these clinicians.

© 2026 The Peptide Association. All rights reserved. Content on this site is protected under applicable intellectual property laws. The Peptide Association is not a medical practice.