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Peptide Database

265 therapeutic peptides with research summaries, clinical findings, and regulatory status.

Showing 1–15 of 15 in CardiovascularClear filters
CardiovascularFDA Approved

Eptifibatide (Integrilin)

A synthetic cyclic heptapeptide modeled after the KGD (Lys-Gly-Asp) disintegrin sequence found in the venom of the southeastern pygmy rattlesnake…

Intravenous
CardiovascularFDA Approved

Nesiritide (Natrecor)

A recombinant form of human B-type natriuretic peptide (BNP), a 32-amino acid peptide naturally produced by ventricular cardiomyocytes in response to…

Intravenous
CardiovascularFDA Approved

Angiotensin II (Giapreza)

A synthetic form of the endogenous octapeptide angiotensin II, the primary effector of the renin-angiotensin system. Angiotensin II acts on AT1…

Intravenous
CardiovascularInvestigational

Serelaxin (Relaxin-2)

Serelaxin is a recombinant form of human relaxin-2, a naturally occurring peptide hormone composed of two chains linked by disulfide bonds. It acts…

Intravenous
CardiovascularInvestigational

Carperitide (h-ANP)

Carperitide is a recombinant form of human atrial natriuretic peptide consisting of 28 amino acids. It activates guanylyl cyclase A receptors…

Intravenous
CardiovascularIn Clinical Trials

Ularitide (Urodilatin)

Ularitide is a synthetic 32-amino acid peptide analogue of urodilatin, a natriuretic peptide produced in renal tubular cells. It binds to guanylyl…

Intravenous
CardiovascularResearch Phase

Atrial Natriuretic Peptide (ANP)

Atrial natriuretic peptide is a 28-amino acid endogenous hormone secreted primarily by atrial cardiomyocytes in response to atrial stretch and volume…

Endogenous
CardiovascularFDA Approved

Brain Natriuretic Peptide (BNP)

Brain natriuretic peptide, despite its name, is a 32-amino acid hormone secreted predominantly by ventricular cardiomyocytes in response to…

Intravenous
CardiovascularResearch Phase

C-type Natriuretic Peptide (CNP)

C-type natriuretic peptide is a 22-amino acid member of the natriuretic peptide family that selectively activates natriuretic peptide receptor B…

Endogenous
CardiovascularInvestigational

Urocortin 1

Urocortin 1 is a 40-amino acid peptide belonging to the corticotropin-releasing factor (CRF) family. It binds to both CRF receptor 1 and CRF receptor…

Intravenous
CardiovascularResearch Phase

Urocortin 2

Urocortin 2 is a 38-amino acid peptide member of the corticotropin-releasing factor family with selective affinity for CRF receptor 2. It exerts…

Intravenous
CardiovascularResearch Phase

Urocortin 3

Urocortin 3, also known as stresscopin, is a 38-amino acid peptide with high selectivity for CRF receptor 2. It produces vasodilation and increases…

Intravenous
CardiovascularInvestigational

Adrenomedullin

Adrenomedullin is a 52-amino acid peptide hormone produced by vascular endothelial and smooth muscle cells with potent vasodilatory and natriuretic…

Intravenous
CardiovascularInvestigational

Angiotensin (1-7)

Angiotensin (1-7) is a seven-amino acid peptide component of the renin-angiotensin system formed through cleavage of angiotensin II by ACE2 or from…

Subcutaneous injection, Intravenous, Oral
CardiovascularResearch Phase

Apelin-13

Apelin-13 is a 13-amino acid endogenous peptide that represents the most potent and abundant isoform of the apelin family. It acts as the ligand for…

Intravenous

All 265 peptides

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Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association reviews licensure but does not employ or directly supervise these clinicians.

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