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Peptide Database

265 therapeutic peptides with research summaries, clinical findings, and regulatory status.

Showing 1–18 of 18 in OncologyClear filters
OncologyFDA Approved

Carfilzomib (Kyprolis)

A tetrapeptide epoxyketone proteasome inhibitor that irreversibly binds the chymotrypsin-like (beta5) subunit of the 20S proteasome. By blocking…

Intravenous
OncologyFDA Approved

Bortezomib (Velcade)

A modified dipeptidyl boronic acid that reversibly inhibits the chymotrypsin-like activity of the 26S proteasome. Bortezomib disrupts the…

Subcutaneous injection, Intravenous
OncologyFDA Approved

Lutetium-177 dotatate (Lutathera)

A radiolabeled somatostatin analog consisting of the peptide DOTA-Tyr3-octreotate chelated to the beta-emitting radioisotope lutetium-177. Lutathera…

Intravenous
OncologyFDA Approved

Leuprolide (Lupron) - Oncology

A GnRH agonist used in oncology for androgen deprivation therapy (ADT) in prostate cancer and hormone suppression in premenopausal breast cancer.…

Intramuscular injection (depot), Subcutaneous injection
OncologyFDA Approved

Degarelix (Firmagon)

Degarelix is a synthetic decapeptide gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of advanced prostate cancer.…

Subcutaneous injection
OncologyFDA Approved

Triptorelin (Trelstar)

Triptorelin is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH) that functions as a long-acting GnRH agonist. Following an…

Intramuscular injection
OncologyIn Clinical Trials

Buserelin (Suprefact)

Buserelin is a synthetic nonapeptide analogue of gonadotropin-releasing hormone (GnRH) that acts as a potent GnRH agonist. It binds with high…

Subcutaneous injection, Intranasal
OncologyFDA Approved

Histrelin (Vantas)

Histrelin is a synthetic nonapeptide analogue of gonadotropin-releasing hormone (GnRH) that functions as a GnRH agonist. The peptide is administered…

Subcutaneous implant
OncologyFDA Approved

Abarelix (Plenaxis)

Abarelix is a synthetic decapeptide that functions as a gonadotropin-releasing hormone (GnRH) receptor antagonist. It competitively blocks pituitary…

Intramuscular injection
OncologyFDA Approved

Elagolix (Orilissa)

Elagolix is a small molecule non-peptide gonadotropin-releasing hormone (GnRH) receptor antagonist administered orally. While not a peptide itself…

Oral
OncologyFDA Approved

Relugolix (Orgovyx)

Relugolix is an orally bioavailable non-peptide gonadotropin-releasing hormone (GnRH) receptor antagonist. Although it is not a peptide, it exerts…

Oral
OncologyFDA Approved

177Lu-PSMA-617 (Pluvicto)

177Lu-PSMA-617 is a radioligand therapeutic consisting of a small peptide-based ligand targeting prostate-specific membrane antigen (PSMA) conjugated…

Intravenous
OncologyFDA Approved

Somatostatin (Native)

Somatostatin is a naturally occurring cyclic tetradecapeptide hormone produced by neuroendocrine cells throughout the body, including the…

Intravenous
OncologyInvestigational

Vapreotide

Vapreotide is a synthetic octapeptide analog of somatostatin with enhanced selectivity for somatostatin receptor subtypes 2 and 5. It exerts…

Subcutaneous injection, Intravenous
OncologyIn Clinical Trials

Vantictumab

Vantictumab is a fully human monoclonal antibody that targets multiple Frizzled receptors involved in the Wnt signaling pathway. By blocking Frizzled…

Intravenous
OncologyFDA Approved

Tirbanibulin (Klisyri)

Tirbanibulin is a small molecule synthetic peptide mimetic that inhibits tubulin polymerization and disrupts Src kinase signaling pathways. It is…

Topical
OncologyIn Clinical Trials

Plitidepsin (Aplidin)

Plitidepsin is a cyclic depsipeptide originally isolated from the Mediterranean tunicate Aplidium albicans and now produced synthetically. It targets…

Intravenous
OncologyIn Clinical Trials

Melphalan Flufenamide (Pepaxto)

Melphalan flufenamide is a first-in-class peptide-drug conjugate that links the alkylating agent melphalan to a dipeptide carrier. The dipeptide…

Intravenous

All 265 peptides

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Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association reviews licensure but does not employ or directly supervise these clinicians.

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