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The compound database

Peptide Database

264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.

FDA-approved
90
FDA-approved
Awaiting FDA
8
Awaiting FDA
No lawful pathway
166
No lawful pathway
1–36 of 53 · Research PhaseClear filters
  1. 001

    TB-500 (Thymosin Beta-4)

    Thymosin Beta-4 (Tβ4) is a 43-amino acid actin-sequestering protein involved in cell migration and tissue repair. Products sold as TB-500 have been found to…

    Recovery · Research Phase · Subcutaneous injection

    Awaiting FDA
  2. 002

    P21 (Peptide)

    A small synthetic peptide (P021) derived from the most active region of ciliary neurotrophic factor (CNTF), with an adamantylated glycine added to improve…

    Cognitive · Research Phase · Subcutaneous injection, Intranasal

    No lawful pathway
  3. 003

    MOTS-c

    A 16-amino acid mitochondrial-derived peptide encoded by a short open reading frame in the 12S rRNA gene of mitochondrial DNA. In mice and cells, MOTS-c…

    Longevity · Research Phase · Subcutaneous injection

    No lawful pathway
  4. 004

    Humanin

    A 24-amino acid mitochondrial-derived peptide whose coding sequence is nearly identical to a region of the mitochondrial 16S rRNA gene. Humanin acts as a…

    Longevity · Research Phase · Subcutaneous injection, Intravenous

    No lawful pathway
  5. 005

    FOXO4-DRI

    A D-retro-inverso peptide designed to disrupt the interaction between FOXO4 and p53 in senescent cells. FOXO4 helps senescent cells avoid apoptosis by binding…

    Longevity · Research Phase · Subcutaneous injection, Intravenous

    No lawful pathway
  6. 006

    Thymulin

    A zinc-containing nonapeptide (facteur thymique serique) produced exclusively by thymic epithelial cells, whose biological activity depends on bound zinc.…

    Immune · Research Phase · Subcutaneous injection, Intranasal

    No lawful pathway
  7. 007

    KPV

    A C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone that retains anti-inflammatory activity without melanogenic effects. In…

    Immune · Research Phase · Oral, Topical, Subcutaneous injection

    No lawful pathway
  8. 008

    Mod GRF 1-29 (CJC-1295 no DAC)

    Modified GRF 1-29 is a synthetic analogue of the first 29 amino acids of growth hormone-releasing hormone (GHRH) with four amino acid substitutions, the same…

    Hormone · Research Phase · Subcutaneous injection

    No lawful pathway
  9. 009

    Obestatin

    Obestatin is a 23-amino acid peptide derived from the same precursor as ghrelin, preproghrelin. It was initially reported to oppose ghrelin by suppressing food…

    Hormone · Research Phase · Subcutaneous injection, Intravenous

    No lawful pathway
  10. 010

    Pentadeca Arginate (PDA)

    Pentadeca Arginate (PDA) is a name used by compounding pharmacies and peptide suppliers for a synthetic 15-amino acid peptide, commonly marketed as a variant…

    Recovery · Research Phase · Subcutaneous injection, Topical

    No lawful pathway
  11. 011

    Thymosin Beta-4 Fragment (TB4-Frag)

    Thymosin Beta-4 fragments are short active segments of the 43-amino acid protein thymosin beta-4. The best studied are the N-terminal tetrapeptide Ac-SDKP…

    Recovery · Research Phase · Subcutaneous injection, Topical

    No lawful pathway
  12. 012

    Matrikine Peptides

    Matrikine peptides are bioactive fragments released from extracellular matrix proteins during tissue remodeling or injury. These sequences, derived from…

    Recovery · Research Phase · Topical, Subcutaneous injection

    No lawful pathway
  13. 013

    AHK-Cu (Copper Tripeptide-3)

    AHK-Cu is a synthetic copper-binding tripeptide consisting of alanine-histidine-lysine complexed with copper ions. It is structurally similar to GHK-Cu but…

    Recovery · Research Phase · Topical

    No lawful pathway
  14. 014

    Dihexa

    Dihexa (N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, also called PNB-0408) is a small synthetic angiotensin IV analogue rather than a true hexapeptide. Its…

    Cognitive · Research Phase · Oral, Subcutaneous injection

    No lawful pathway
  15. 015

    Spadin

    Spadin is a 17-amino acid peptide derived from the propeptide released during maturation of sortilin, also known as neurotensin receptor 3. It blocks the…

    Cognitive · Research Phase · Intravenous, Intranasal

    No lawful pathway
  16. 016

    N-acetyl Semax Amidate

    N-acetyl Semax Amidate is a modified form of Semax, a heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) combining the ACTH 4-7 sequence with a C-terminal Pro-Gly-Pro…

    Cognitive · Research Phase · Intranasal, Subcutaneous injection

    No lawful pathway
  17. 017

    N-acetyl Selank Amidate

    N-acetyl Selank Amidate is a modified form of Selank, a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) built on the immunomodulatory peptide tuftsin with…

    Cognitive · Research Phase · Intranasal

    No lawful pathway
  18. 018

    Bromantane-adjacent Peptides

    Bromantane-adjacent peptides refer to a theoretical class of compounds that might share functional goals with bromantane, a synthetic adamantane derivative…

    Cognitive · Research Phase · Not established

    No lawful pathway
  19. 019

    Orexin B

    Orexin B (hypocretin-2) is a 28-amino acid neuropeptide derived from the same precursor as orexin A and produced in hypothalamic neurons; central…

    Cognitive · Research Phase · Intracerebroventricular

    No lawful pathway
  20. 020

    Vialox (Pentapeptide-3)

    Vialox (pentapeptide-3) is a synthetic pentapeptide marketed as a topical agent that interferes with acetylcholine receptor activation to reduce muscle…

    Dermatology · Research Phase · Topical

    No lawful pathway
  21. 021

    Haloxyl (Chrysin + Palmitoyl Peptides)

    Haloxyl is a proprietary cosmetic ingredient combining chrysin, a naturally occurring flavone, with palmitoyl peptides, marketed to reduce under-eye dark…

    Dermatology · Research Phase · Topical

    No lawful pathway
  22. 022

    Eyeseryl (Acetyl Tetrapeptide-5)

    Acetyl Tetrapeptide-5 is a synthetic tetrapeptide modified with an acetyl group to improve stability. It is marketed to reduce under-eye puffiness and fluid…

    Dermatology · Research Phase · Topical

    No lawful pathway
  23. 023

    Trylagen (Tripeptide-10 Complex)

    Trylagen is a proprietary cosmetic complex that incorporates Tripeptide-10 Citrulline along with other peptide and protein components, marketed to support…

    Dermatology · Research Phase · Topical

    No lawful pathway
  24. 024

    Myristoyl Pentapeptide-17

    Myristoyl Pentapeptide-17 is a lipopeptide composed of a pentapeptide sequence conjugated to myristic acid, intended to improve penetration into the skin and…

    Dermatology · Research Phase · Topical

    No lawful pathway
  25. 025

    Palmitoyl Tripeptide-1

    Palmitoyl Tripeptide-1 (also called Pal-GHK) is a synthetic lipopeptide in which the tripeptide glycyl-histidyl-lysine (GHK) is linked to palmitic acid to…

    Dermatology · Research Phase · Topical

    No lawful pathway
  26. 026

    Melitane (Acetyl Hexapeptide-1)

    Acetyl Hexapeptide-1 (trade name Melitane) is a synthetic hexapeptide cosmetic ingredient designed as a biomimetic of alpha-melanocyte-stimulating hormone…

    Dermatology · Research Phase · Topical

    No lawful pathway
  27. 027

    Bursin

    Bursin is a tripeptide amide (Lys-His-Gly-NH2) originally isolated from the bursa of Fabricius in chickens, where it was described as a selective…

    Immune · Research Phase · Subcutaneous injection

    No lawful pathway
  28. 028

    Tuftsin

    Tuftsin is a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) released by enzymatic processing from the Fc domain of the immunoglobulin G heavy chain. It…

    Immune · Research Phase · Subcutaneous injection, Intravenous

    No lawful pathway
  29. 029

    Beta-Defensin 2

    Human beta-defensin 2 (hBD-2) is a 41-amino-acid cationic antimicrobial peptide first described in psoriatic skin and produced by epithelial cells in response…

    Immune · Research Phase · Topical, Subcutaneous injection

    No lawful pathway
  30. 030

    Beta-Defensin 3

    Human beta-defensin 3 (hBD-3) is a cationic antimicrobial peptide of roughly 45 amino acids. Unlike hBD-1 and hBD-2, it kills Gram-positive organisms such as…

    Immune · Research Phase · Topical, Subcutaneous injection

    No lawful pathway
  31. 031

    Granulysin

    Granulysin is an antimicrobial and cytolytic protein produced by human cytotoxic T lymphocytes and natural killer cells, and it is structurally related to…

    Immune · Research Phase · Intravenous, Subcutaneous injection

    No lawful pathway
  32. 032

    C-type Natriuretic Peptide (CNP)

    C-type natriuretic peptide (CNP) is a 22-amino acid member of the natriuretic peptide family that signals mainly through natriuretic peptide receptor B (NPR-B)…

    Cardiovascular · Research Phase · Endogenous

    No lawful pathway
  33. 033

    Glucagon Receptor Antagonist Peptides

    Glucagon receptor antagonist peptides are molecules designed to block the glucagon receptor and prevent glucagon-driven hepatic glucose output. Most are…

    Gastrointestinal · Research Phase · Subcutaneous injection

    No lawful pathway
  34. 034

    Guanylin

    Guanylin is a 15-amino acid peptide hormone that activates guanylate cyclase-C (GC-C) receptors on intestinal epithelial cells. Binding raises intracellular…

    Gastrointestinal · Research Phase · Endogenous peptide

    No lawful pathway
  35. 035

    Leu-Enkephalin

    Leu-enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Leu) identified in 1975 as one of the two enkephalins, natural ligands for opiate receptors. Enkephalins are…

    Pain · Research Phase · Endogenous peptide

    No lawful pathway
  36. 036

    Endomorphin-1

    Endomorphin-1 is an amidated tetrapeptide (Tyr-Pro-Trp-Phe-NH2) isolated from brain in 1997 that binds the mu-opioid receptor with high affinity and about…

    Pain · Research Phase · Endogenous peptide

    No lawful pathway

Index · all 264 peptides, A–Z

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