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The compound database
Peptide Databasepage 2
264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.
- FDA-approved
- 90
- FDA-approved
- Awaiting FDA
- 8
- Awaiting FDA
- No lawful pathway
- 166
- No lawful pathway
- 037
Semax
A synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) that combines the ACTH(4-7) fragment with a stabilizing Pro-Gly-Pro tail and is described as an analog…
Cognitive · Investigational · Intranasal
Awaiting FDA - 038
Selank
A synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) built from the endogenous tetrapeptide tuftsin with an added Pro-Gly-Pro sequence for stability. In…
Cognitive · Investigational · Intranasal
Awaiting FDA - 039
Cerebrolysin
A porcine brain-derived preparation of low-molecular-weight peptides and amino acids with proposed neurotrophic and neuroprotective properties. In transgenic…
Cognitive · In Clinical Trials · Intravenous, Intramuscular injection
No lawful pathway - 040
P21 (Peptide)
A small synthetic peptide (P021) derived from the most active region of ciliary neurotrophic factor (CNTF), with an adamantylated glycine added to improve…
Cognitive · Research Phase · Subcutaneous injection, Intranasal
No lawful pathway - 041
Epithalon (Epitalon)
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) designed from the amino acid composition of epithalamin, a peptide extract of the pineal gland. In cell culture…
Longevity · Investigational · Subcutaneous injection, Intravenous
No lawful pathway - 042
MOTS-c
A 16-amino acid mitochondrial-derived peptide encoded by a short open reading frame in the 12S rRNA gene of mitochondrial DNA. In mice and cells, MOTS-c…
Longevity · Research Phase · Subcutaneous injection
No lawful pathway - 043
Humanin
A 24-amino acid mitochondrial-derived peptide whose coding sequence is nearly identical to a region of the mitochondrial 16S rRNA gene. Humanin acts as a…
Longevity · Research Phase · Subcutaneous injection, Intravenous
No lawful pathway - 044
NAD+ Precursors (NMN)
Nicotinamide mononucleotide (NMN) is a direct biosynthetic precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for cellular metabolism…
Longevity · In Clinical Trials · Oral, Intravenous, Sublingual
No lawful pathway - 045
SS-31 (Elamipretide)
A mitochondria-targeted tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that selectively binds cardiolipin in the inner mitochondrial membrane. In laboratory…
Longevity · FDA Approved · Subcutaneous injection, Intravenous
FDA-approved - 046
FOXO4-DRI
A D-retro-inverso peptide designed to disrupt the interaction between FOXO4 and p53 in senescent cells. FOXO4 helps senescent cells avoid apoptosis by binding…
Longevity · Research Phase · Subcutaneous injection, Intravenous
No lawful pathway - 047
Thymalin
A peptide bioregulator extracted from bovine thymus, consisting of a polypeptide complex that regulates immune function. Thymalin increases the functional…
Immune · Investigational · Intramuscular injection
No lawful pathway - 048
LL-37
The only human cathelicidin antimicrobial peptide, a 37-amino acid cationic peptide cleaved from the precursor protein hCAP18. LL-37 has broad antimicrobial…
Immune · Investigational · Subcutaneous injection, Topical
No lawful pathway - 049
VIP (Vasoactive Intestinal Peptide)
A 28-amino acid neuropeptide widely distributed in the central and peripheral nervous systems and immune cells. VIP acts through VPAC1 and VPAC2 receptors and…
Immune · Investigational · Intranasal, Intravenous, Subcutaneous injection
No lawful pathway - 050
Thymosin Alpha 1 (Zadaxin)
A 28-amino acid peptide originally isolated from thymic tissue (thymosin fraction 5) and used as an immunomodulator under the name thymalfasin. Thymosin alpha…
Immune · In Clinical Trials · Subcutaneous injection
Awaiting FDA - 051
Thymopentin (TP-5)
A synthetic pentapeptide (Arg-Lys-Asp-Val-Tyr) corresponding to residues 32-36 of thymopoietin, a thymic hormone involved in T-cell differentiation.…
Immune · Investigational · Subcutaneous injection, Intramuscular injection
No lawful pathway - 052
Thymulin
A zinc-containing nonapeptide (facteur thymique serique) produced exclusively by thymic epithelial cells, whose biological activity depends on bound zinc.…
Immune · Research Phase · Subcutaneous injection, Intranasal
No lawful pathway - 053
KPV
A C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone that retains anti-inflammatory activity without melanogenic effects. In…
Immune · Research Phase · Oral, Topical, Subcutaneous injection
No lawful pathway - 054
Enfuvirtide (Fuzeon)
A 36-amino acid synthetic peptide that inhibits HIV-1 entry into CD4+ T-cells by blocking gp41-mediated membrane fusion. Enfuvirtide binds the first heptad…
Antimicrobial · FDA Approved · Subcutaneous injection (twice daily)
FDA-approved - 055
Melanotan II
A synthetic cyclic analog of alpha-melanocyte stimulating hormone (alpha-MSH) that non-selectively activates melanocortin receptors. Through MC1R it stimulates…
Performance · Investigational · Subcutaneous injection
No lawful pathway - 056
Teriparatide (Forteo)
A recombinant form of the first 34 amino acids of human parathyroid hormone (PTH 1-34). When given intermittently by daily subcutaneous injection, teriparatide…
Bone · FDA Approved · Subcutaneous injection (daily)
FDA-approved - 057
Abaloparatide (Tymlos)
A synthetic 34-amino acid peptide analog of parathyroid hormone-related protein (PTHrP 1-34). In cell studies abaloparatide binds more selectively than PTH…
Bone · FDA Approved · Subcutaneous injection (daily)
FDA-approved - 058
Calcitonin
A 32-amino acid peptide hormone naturally produced by the parafollicular C-cells of the thyroid gland. Calcitonin inhibits osteoclast activity, reducing bone…
Bone · FDA Approved · Intranasal, Subcutaneous injection, Intramuscular injection
FDA-approved - 059
Vosoritide (Voxzogo)
A C-type natriuretic peptide (CNP) analog that acts as an agonist at natriuretic peptide receptor B (NPR-B) on growth plate chondrocytes. Achondroplasia is…
Bone · FDA Approved · Subcutaneous injection (daily)
FDA-approved - 060
Vasopressin (ADH)
A nine-amino acid cyclic peptide hormone (arginine vasopressin) produced in the hypothalamus and released from the posterior pituitary. Vasopressin acts on V1a…
Renal · FDA Approved · Intravenous, Intramuscular injection, Subcutaneous injection
FDA-approved - 061
Desmopressin (DDAVP)
A synthetic analog of vasopressin (1-deamino-8-D-arginine vasopressin) with selective V2 receptor activity and minimal vasopressor activity. The deamination at…
Renal · FDA Approved · Intranasal, Oral, Subcutaneous injection, Intravenous
FDA-approved - 062
Terlipressin
A synthetic vasopressin analog and prodrug that is converted in the body to lysine-vasopressin. Terlipressin acts mainly on V1 receptors to constrict…
Renal · FDA Approved · Intravenous
FDA-approved - 063
Eptifibatide (Integrilin)
A synthetic cyclic heptapeptide modeled on barbourin, a disintegrin from the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri) that…
Cardiovascular · FDA Approved · Intravenous
FDA-approved - 064
Nesiritide (Natrecor)
A recombinant form of human B-type natriuretic peptide (BNP), a 32-amino acid peptide produced by ventricular cardiomyocytes in response to volume overload and…
Cardiovascular · FDA Approved · Intravenous
FDA-approved - 065
Angiotensin II (Giapreza)
A synthetic form of the endogenous octapeptide angiotensin II, the main effector of the renin-angiotensin system. Angiotensin II acts on AT1 receptors on…
Cardiovascular · FDA Approved · Intravenous
FDA-approved - 066
Bivalirudin (Angiomax)
A synthetic 20-amino acid peptide analog of hirudin that acts as a specific, reversible direct thrombin inhibitor, binding both fluid-phase and clot-bound…
Hematology · FDA Approved · Intravenous
FDA-approved - 067
Romiplostim (Nplate)
A thrombopoietin (TPO) receptor agonist built as a peptibody: TPO-mimetic peptides fused to the Fc portion of human IgG1. It has a similar mechanism of action…
Hematology · FDA Approved · Subcutaneous injection (weekly)
FDA-approved - 068
Pegcetacoplan (Empaveli)
A pegylated cyclic peptide that inhibits complement component C3 and C3b, acting upstream of C5 in the complement cascade. Because C5 inhibitors control…
Hematology · FDA Approved · Subcutaneous infusion
FDA-approved - 069
Carfilzomib (Kyprolis)
A tetrapeptide epoxyketone proteasome inhibitor that binds the proteasome irreversibly, with minimal off-target inhibition of other proteases in preclinical…
Oncology · FDA Approved · Intravenous
FDA-approved - 070
Bortezomib (Velcade)
A dipeptidyl boronic acid that selectively and reversibly inhibits the 26S proteasome, disrupting the ubiquitin-proteasome pathway that degrades many…
Oncology · FDA Approved · Subcutaneous injection, Intravenous
FDA-approved - 071
Lutetium-177 dotatate (Lutathera)
A radiolabeled somatostatin analog consisting of the peptide DOTA-Tyr3-octreotate chelated to the beta-emitting radioisotope lutetium-177. It binds…
Oncology · FDA Approved · Intravenous
FDA-approved - 072
Leuprolide (Lupron) - Oncology
A GnRH agonist used in oncology for androgen deprivation therapy (ADT) in prostate cancer. Continuous administration downregulates pituitary GnRH receptors…
Oncology · FDA Approved · Intramuscular injection (depot), Subcutaneous injection
FDA-approved
Index · all 264 peptides, A–Z
- 177Lu-PSMA-617 (Pluvicto)
- Abaloparatide (Tymlos)
- Abarelix (Plenaxis)
- ACE-031 (Ramatercept)
- ACTH (4-10) Analogs
- Adrenomedullin
- Afamelanotide (Scenesse)
- AHK-Cu (Copper Tripeptide-3)
- Albiglutide (Tanzeum)
- Alpha-Defensin 5
- Alpha-MSH
- Amycretin
- Anamorelin (Adlumiz)
- Angiotensin (1-7)
- Angiotensin II (Giapreza)
- AOD-9604
- Apelin-13
- Apraglutide
- ARA-290
- Argireline (Acetyl Hexapeptide-8)
- Atosiban
- Atrial Natriuretic Peptide (ANP)
- Beinaglutide
- Beta-Defensin 2
- Beta-Defensin 3
- Biopeptide CL (Palmitoyl Tripeptide-5)
- Bioregulator Peptides (Khavinson)
- Bivalirudin (Angiomax)
- BMP-2 (Bone Morphogenetic Protein-2)
- BMP-7 (Osteogenic Protein-1)
- Body Protection Compound (BPC) Variants
- Bombesin Analog Tracers
- Bortezomib (Velcade)
- BPC-157
- Brain Natriuretic Peptide (BNP)
- Bromantane-adjacent Peptides
- Bursin
- Buserelin (Suprefact)
- C-type Natriuretic Peptide (CNP)
- Cagrilintide
- CagriSema
- Calcitonin
- Calcitonin Gene-Related Peptide (CGRP)
- Capromorelin (Entyce)
- Carbetocin
- Carfilzomib (Kyprolis)
- Carperitide (h-ANP)
- Cathelicidin LL-37 Fragments
- Cerebrolysin
- Cetrorelix (Cetrotide)
- Cetrorelix (Cetrotide) Analog
- Cholecystokinin (CCK)
- Choriogonadotropin Alfa (Ovidrel)
- Chrysalin (TP508)
- CJC-1295
- Colistin (Polymyxin E)
- Collagen Tripeptide F (CTP-F)
- Conantokin-G
- Copper Peptide (Prezatide Copper Acetate)
- Corifollitropin Alfa (Elonva)
- Cortexin
- Cosyntropin (Cortrosyn)
- Cotadutide
- Dalargin
- Danuglipron
- Decorinyl (Tripeptide-10 Citrulline)
- Defensin HNP-1
- Degarelix (Firmagon)
- Deltorphin
- Dermorphin
- Desmopressin (DDAVP)
- Difelikefalin (Korsuva)
- Dihexa
- DOTATATE (Ga-68)
- DSIP (Delta Sleep-Inducing Peptide)
- Dulaglutide (Trulicity)
- Dynorphin A
- Ecnoglutide
- Efinopegdutide
- Elagolix (Orilissa)
- Eltrombopag Peptide Mimetics
- Endomorphin-1
- Endomorphin-2
- Enfuvirtide (Fuzeon)
- Enlicitide
- Epithalon (Epitalon)
- Eptifibatide (Integrilin)
- Exenatide (Byetta/Bydureon)
- Eyeseryl (Acetyl Tetrapeptide-5)
- FGL Peptide
- Follistatin-344
- Follitropin Alfa (Gonal-F)
- FOXO4-DRI
- Gadopentetate Peptide Conjugates
- Galanin
- Ganirelix
- Gastrin
- Gerontin (Pineal Gland Extract)
- GHK (Glycyl-Histidyl-Lysine)
- GHK-Cu
- Ghrelin (Native)
- Ghrelin Receptor Antagonists
- GHRH (Sermorelin 1-44)
- GHRP-1
- GHRP-2
- GHRP-6
- Glepaglutide
- Glucagon
- Glucagon Receptor Antagonist Peptides
- Gonadorelin (GnRH)
- Gonadotropin Releasing Hormone (GnRH) Agonists
- Goserelin (Zoladex)
- Gramicidin S
- Granulysin
- Guanylin
- Haloxyl (Chrysin + Palmitoyl Peptides)
- Hepcidin
- Hexarelin
- Histrelin (Vantas)
- Humanin
- Icatibant (Firazyr)
- IGF-1 DES (1-3)
- IGF-1 LR3 (Long-Arg3)
- Imuthiol (Diethyldithiocarbamate)
- Indolicidin
- Intranasal Insulin
- Ipamorelin
- Iseganan (IB-367)
- Kisspeptin
- Klotho Peptide
- KPV
- Lactoferricin
- Lanreotide (Somatuline Depot)
- Larazotide
- Leu-Enkephalin
- Leuphasyl (Pentapeptide-18)
- Leuprolide (Lupron)
- Leuprolide (Lupron) - Oncology
- Linaclotide (Linzess)
- Liraglutide (Saxenda/Victoza)
- Lixisenatide (Adlyxin)
- LL-37
- Lonapegsomatropin (Skytrofa)
- Lutetium-177 dotatate (Lutathera)
- Macimorelin (Macrilen)
- Magainin 2
- Matrikine Peptides
- Matrixyl (Palmitoyl Pentapeptide-4)
- Matrixyl 3000
- Matrixyl Synthe'6 (Palmitoyl Tripeptide-38)
- Mazdutide
- Mecasermin (Increlex)
- Melanotan II
- Melitane (Acetyl Hexapeptide-1)
- Melphalan Flufenamide (Pepaxto)
- Menotropin (Menopur)
- Met-Enkephalin
- MGF (Mechano Growth Factor)
- Mitochondrial-Targeted Peptides (MTP)
- MK-677 (Ibutamoren)
- Mod GRF 1-29 (CJC-1295 no DAC)
- Motilin
- MOTS-c
- Myristoyl Pentapeptide-17
- N-acetyl Selank Amidate
- N-acetyl Semax Amidate
- NAD+ Precursors (NMN)
- Nafarelin (Synarel)
- NAP (Davunetide)
- Nemifitide
- Nesiritide (Natrecor)
- Neuropeptide FF
- Neurotensin
- Nexagon (Gap Junction Peptide)
- Nisin
- Nociceptin / Orphanin FQ
- Obestatin
- Octreotide (Sandostatin)
- Omiganan
- OP-1 / BMP-7
- Orexin A
- Orexin B
- Orforglipron
- Osteogenic Growth Peptide (OGP)
- Oxytocin
- P21 (Peptide)
- Palmitoyl Tripeptide-1
- Palmitoylethanolamide (PEA)
- Pasireotide (Signifor)
- PEG-MGF
- Pegcetacoplan (Empaveli)
- Peginesatide (Omontys)
- Pegvisomant (Somavert)
- Pemvidutide
- Pentadeca Arginate (PDA)
- Pentagastrin
- Pentosan Polysulfate (Elmiron)
- Peptide YY (PYY 3-36)
- Pexiganan (MSI-78)
- Pinealon
- Plecanatide (Trulance)
- Plitidepsin (Aplidin)
- Polymyxin B
- Pramlintide (Symlin)
- PT-141 (Bremelanotide / Vyleesi)
- PTH (1-34) Analogs
- Relamorelin
- Relugolix (Orgovyx)
- Retatrutide
- RGD Peptide Tracers
- Rigin (Palmitoyl Tetrapeptide-7)
- Romiplostim (Nplate)
- Sclerostin Antibodies (Romosozumab)
- Secretin
- Selank
- Semaglutide (Ozempic/Wegovy)
- Semax
- Serelaxin (Relaxin-2)
- Sermorelin
- Setmelanotide (Imcivree)
- Sinapultide (KL4 Surfactant)
- Sirtuin-Activating Peptides
- SNAP-8 (Acetyl Octapeptide-3)
- Somapacitan (Sogroya)
- Somatostatin (Native)
- Somatropin (Genotropin)
- Spadin
- Splenopentin
- SS-31 (Elamipretide)
- Survodutide
- SYN-AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate)
- Tabimorelin
- Taspoglutide
- TB-500 (Thymosin Beta-4)
- Teduglutide (Gattex)
- Teriparatide (Forteo)
- Terlipressin
- Tesamorelin (Egrifta)
- Thrombopoietin (TPO)
- Thymalin
- Thymogen (Glutamyl-Tryptophan)
- Thymopentin (TP-5)
- Thymosin Alpha 1 (Zadaxin)
- Thymosin Beta-4 Fragment (TB4-Frag)
- Thymostimulin (TP-1)
- Thymulin
- Tirbanibulin (Klisyri)
- Tirzepatide (Mounjaro/Zepbound)
- Triptorelin (Trelstar)
- Trylagen (Tripeptide-10 Complex)
- Tuftsin
- Ularitide (Urodilatin)
- Urocortin 1
- Urocortin 2
- Urocortin 3
- Uroguanylin (Dolcanatide)
- Vantictumab
- Vapreotide
- Vasopressin (ADH)
- Vialox (Pentapeptide-3)
- Vilon (Lys-Glu)
- VIP (Vasoactive Intestinal Peptide)
- Vosoritide (Voxzogo)
- Ziconotide (Prialt)
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Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association checks each clinician’s NPI record but does not employ or directly supervise these clinicians.
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