Peptide DatabasePage 7

265 therapeutic peptides with research summaries, clinical findings, and regulatory status.

Showing 217–252 of 265
PainResearch Phase

Dermorphin

Dermorphin is a heptapeptide opioid agonist originally isolated from the skin of South American Phyllomedusa frogs. It exhibits high selectivity and…

Intracerebroventricular, Subcutaneous injection
PainResearch Phase

Deltorphin

Deltorphin is a heptapeptide opioid agonist also derived from Phyllomedusa frog skin secretions, characterized by high selectivity for delta-opioid…

Intracerebroventricular, Subcutaneous injection
PainResearch Phase

Neuropeptide FF

Neuropeptide FF (NPFF) is an octapeptide belonging to the RFamide family, characterized by an arginine-phenylalanine-amide motif at the C-terminus.…

Intracerebroventricular, Subcutaneous injection
AntimicrobialResearch Phase

Magainin 2

Magainin 2 is a 23-amino acid antimicrobial peptide originally isolated from the skin of the African clawed frog Xenopus laevis. It exerts…

Topical
AntimicrobialIn Clinical Trials

Pexiganan (MSI-78)

Pexiganan is a 22-amino acid synthetic analog of magainin 2 designed to enhance antimicrobial potency and proteolytic stability. It disrupts…

Topical
AntimicrobialIn Clinical Trials

Omiganan

Omiganan is a synthetic 12-amino acid cationic antimicrobial peptide derived from indolicidin, a naturally occurring peptide from bovine neutrophils.…

Topical
AntimicrobialInvestigational

Iseganan (IB-367)

Iseganan is a 17-amino acid synthetic analog of protegrin, a naturally occurring antimicrobial peptide found in porcine leukocytes. It disrupts…

Oral rinse
AntimicrobialResearch Phase

Defensin HNP-1

Human neutrophil peptide 1 (HNP-1) is a 30-amino acid alpha-defensin produced by neutrophils as part of the innate immune response. It contains three…

Topical, Intravenous
AntimicrobialResearch Phase

Alpha-Defensin 5

Alpha-defensin 5 (HD5) is a 32-amino acid cationic peptide predominantly expressed by Paneth cells in the small intestinal crypts. It contains three…

Oral, Topical
AntimicrobialInvestigational

Lactoferricin

Lactoferricin is a cationic antimicrobial peptide derived from pepsin-mediated cleavage of lactoferrin, an iron-binding glycoprotein found in milk…

Oral, Topical
AntimicrobialInvestigational

Nisin

Nisin is a 34-amino acid polycyclic antibacterial peptide (lantibiotic) produced by Lactococcus lactis. It disrupts bacterial cell wall synthesis and…

Topical, Oral
AntimicrobialInvestigational

Gramicidin S

Gramicidin S is a cyclic decapeptide antibiotic isolated from Bacillus brevis, consisting of two identical pentapeptide sequences joined in a ring…

Topical
AntimicrobialFDA Approved

Polymyxin B

Polymyxin B is a cyclic lipopeptide antibiotic derived from Bacillus polymyxa, consisting of a heptapeptide ring and a tripeptide side chain acylated…

Intravenous, Intrathecal, Topical
AntimicrobialFDA Approved

Colistin (Polymyxin E)

Colistin, also known as polymyxin E, is a cyclic polypeptide antibiotic structurally similar to polymyxin B, produced by Paenibacillus polymyxa. It…

Intravenous, Intramuscular, Inhalation
AntimicrobialResearch Phase

Indolicidin

Indolicidin is a 13-amino acid antimicrobial peptide derived from bovine neutrophils, characterized by a high tryptophan content (five residues). It…

Topical
BoneFDA Approved

PTH (1-34) Analogs

PTH (1-34) analogs, including teriparatide and abaloparatide, are synthetic peptides corresponding to the 34 N-terminal amino acids of human…

Subcutaneous injection
BoneFDA Approved

Sclerostin Antibodies (Romosozumab)

Romosozumab is a humanized monoclonal antibody that binds and inhibits sclerostin, a glycoprotein produced by osteocytes that negatively regulates…

Subcutaneous injection
BoneResearch Phase

Osteogenic Growth Peptide (OGP)

Osteogenic Growth Peptide is a naturally occurring 14-amino acid peptide identified in serum that promotes osteoblast proliferation and…

Subcutaneous injection
BoneFDA Approved

BMP-2 (Bone Morphogenetic Protein-2)

BMP-2 is a member of the transforming growth factor-beta superfamily, consisting of a homodimeric protein with each monomer containing approximately…

Surgical implantation
BoneFDA Approved

BMP-7 (Osteogenic Protein-1)

BMP-7, also known as osteogenic protein-1 (OP-1), is a member of the bone morphogenetic protein family with a mature homodimeric structure of…

Surgical implantation
BoneResearch Phase

Calcitonin Gene-Related Peptide (CGRP)

Calcitonin gene-related peptide is a 37-amino acid neuropeptide produced by alternative splicing of the calcitonin gene. CGRP acts as a potent…

Intravenous, Subcutaneous injection
LongevityFDA Approved

Gonadotropin Releasing Hormone (GnRH) Agonists

Gonadotropin-releasing hormone agonists are synthetic decapeptide analogues of native GnRH that initially stimulate and then suppress gonadotropin…

Subcutaneous injection, Intramuscular injection, Subcutaneous implant, Intranasal
LongevityResearch Phase

Klotho Peptide

Klotho is a transmembrane protein of approximately 1012 amino acids that exists in membrane-bound and secreted forms, with the soluble ectodomain…

Intravenous
LongevityResearch Phase

Sirtuin-Activating Peptides

Sirtuin-activating peptides represent a class of investigational compounds designed to enhance the enzymatic activity of sirtuins, a family of…

Subcutaneous injection
LongevityIn Clinical Trials

Mitochondrial-Targeted Peptides (MTP)

Mitochondrial-targeted peptides are short synthetic sequences, typically 2 to 8 amino acids, designed to localize to mitochondria and protect against…

Subcutaneous injection, Intravenous
LongevityInvestigational

Thymulin (Zn-FTS)

Thymulin is a nonapeptide hormone secreted by thymic epithelial cells that requires zinc for biological activity and is also referred to as facteur…

Subcutaneous injection
LongevityInvestigational

Gerontin (Pineal Gland Extract)

Gerontin refers to peptide fractions derived from pineal gland extracts studied primarily in Russian gerontology research. These preparations are…

Subcutaneous injection
LongevityInvestigational

Vilon (Lys-Glu)

Vilon is a synthetic dipeptide consisting of lysine and glutamic acid (Lys-Glu) developed as part of the Khavinson bioregulator peptide research…

Subcutaneous injection, Oral
LongevityInvestigational

Bioregulator Peptides (Khavinson)

Bioregulator peptides are a class of short synthetic peptides, typically 2 to 4 amino acids in length, developed by Russian researcher Vladimir…

Subcutaneous injection, Oral, Intramuscular injection
PerformanceResearch Phase

IGF-1 LR3 (Long-Arg3)

IGF-1 LR3 is a synthetic analogue of insulin-like growth factor 1 with an N-terminal extension of 13 amino acids and a substitution of arginine for…

Subcutaneous injection
PerformanceResearch Phase

IGF-1 DES (1-3)

IGF-1 DES (1-3) is a truncated analogue of insulin-like growth factor 1 lacking the first three N-terminal amino acids (glycine-proline-glutamate).…

Subcutaneous injection
PerformanceResearch Phase

MGF (Mechano Growth Factor)

Mechano Growth Factor is a splice variant of the IGF-1 gene expressed in response to mechanical stress on muscle tissue. The peptide contains a…

Intramuscular injection
PerformanceResearch Phase

PEG-MGF

PEG-MGF is a pegylated derivative of Mechano Growth Factor designed to extend systemic half-life through the addition of polyethylene glycol…

Subcutaneous injection
PerformanceResearch Phase

Follistatin-344

Follistatin-344 is a 344-amino acid glycoprotein that functions as a binding protein and endogenous antagonist of myostatin and other members of the…

Intramuscular injection, Gene delivery
PerformanceInvestigational

ACE-031 (Ramatercept)

ACE-031 is a recombinant fusion protein combining the extracellular domain of the activin receptor type IIB with a human IgG1 Fc domain. This soluble…

Subcutaneous injection
ReproductiveFDA Approved

Nafarelin (Synarel)

Nafarelin is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH) with substitutions at positions 6 and 10 that enhance receptor…

Intranasal

All 265 peptides

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