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The compound database

Peptide Databasepage 5

264 therapeutic peptides with research summaries, clinical findings, and regulatory status. Every claim is cited.

FDA-approved
90
FDA-approved
Awaiting FDA
8
Awaiting FDA
No lawful pathway
166
No lawful pathway
145–180 of 264
  1. 145

    Orexin B

    Orexin B (hypocretin-2) is a 28-amino acid neuropeptide derived from the same precursor as orexin A and produced in hypothalamic neurons; central…

    Cognitive · Research Phase · Intracerebroventricular

    No lawful pathway
  2. 146

    Neurotensin

    Neurotensin is a 13-amino acid neuropeptide found in the central nervous system and gastrointestinal tract, where it modulates dopamine neurotransmission…

    Cognitive · Investigational · Intravenous, Intracerebroventricular

    No lawful pathway
  3. 147

    Galanin

    Galanin is a 29 or 30 amino acid neuropeptide widely expressed in the brain, acting through three G protein-coupled receptor subtypes, GalR1, GalR2, and GalR3…

    Cognitive · Investigational · Intravenous

    No lawful pathway
  4. 148

    Argireline (Acetyl Hexapeptide-8)

    Argireline is a synthetic six amino acid peptide (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2) patterned on the N-terminal end of the SNAP-25 protein and designed to mimic…

    Dermatology · Investigational · Topical

    No lawful pathway
  5. 149

    Matrixyl (Palmitoyl Pentapeptide-4)

    Matrixyl is a lipopeptide composed of the pentapeptide sequence Lys-Thr-Thr-Lys-Ser (KTTKS) attached to palmitic acid to improve skin delivery. In vitro work…

    Dermatology · Investigational · Topical

    No lawful pathway
  6. 150

    Matrixyl 3000

    Matrixyl 3000 is a proprietary combination of two lipopeptides, palmitoyl tripeptide-1 (Pal-GHK) and palmitoyl tetrapeptide-7 (Pal-GQPR), marketed to support…

    Dermatology · Investigational · Topical

    No lawful pathway
  7. 151

    Matrixyl Synthe'6 (Palmitoyl Tripeptide-38)

    Palmitoyl tripeptide-38 is a synthetic lipopeptide described as a matrix-repair peptide for photoaged skin. Its supplier markets it as stimulating synthesis of…

    Dermatology · Investigational · Topical

    No lawful pathway
  8. 152

    SYN-AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate)

    SYN-AKE is a synthetic dipeptide derivative modeled on waglerin-1, a peptide from Temple viper venom that blocks the adult muscle-type nicotinic acetylcholine…

    Dermatology · Investigational · Topical

    No lawful pathway
  9. 153

    SNAP-8 (Acetyl Octapeptide-3)

    SNAP-8 is an elongated derivative of Argireline, consisting of eight amino acids (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2) intended to mimic the SNAP-25…

    Dermatology · Investigational · Topical

    No lawful pathway
  10. 154

    Leuphasyl (Pentapeptide-18)

    Leuphasyl is a synthetic pentapeptide (Tyr-D-Ala-Gly-Phe-Leu) modeled on the N-terminal sequence of enkephalin. It is described as a neuromodulatory peptide…

    Dermatology · Investigational · Topical

    No lawful pathway
  11. 155

    Vialox (Pentapeptide-3)

    Vialox (pentapeptide-3) is a synthetic pentapeptide marketed as a topical agent that interferes with acetylcholine receptor activation to reduce muscle…

    Dermatology · Research Phase · Topical

    No lawful pathway
  12. 156

    Rigin (Palmitoyl Tetrapeptide-7)

    Rigin is the tetrapeptide Gly-Gln-Pro-Arg, originally identified as a tuftsin-like fragment of human immunoglobulin G with phagocytosis-stimulating activity…

    Dermatology · Investigational · Topical

    No lawful pathway
  13. 157

    Biopeptide CL (Palmitoyl Tripeptide-5)

    Palmitoyl Tripeptide-5 is a synthetic lipopeptide consisting of a tripeptide sequence conjugated to palmitic acid to improve skin delivery. Its suppliers…

    Dermatology · Investigational · Topical

    No lawful pathway
  14. 158

    Decorinyl (Tripeptide-10 Citrulline)

    Decorinyl (tripeptide-10 citrulline) is a synthetic tetrapeptide designed to mimic the collagen-binding sites of decorin, a small proteoglycan that regulates…

    Dermatology · Investigational · Topical

    No lawful pathway
  15. 159

    Haloxyl (Chrysin + Palmitoyl Peptides)

    Haloxyl is a proprietary cosmetic ingredient combining chrysin, a naturally occurring flavone, with palmitoyl peptides, marketed to reduce under-eye dark…

    Dermatology · Research Phase · Topical

    No lawful pathway
  16. 160

    Eyeseryl (Acetyl Tetrapeptide-5)

    Acetyl Tetrapeptide-5 is a synthetic tetrapeptide modified with an acetyl group to improve stability. It is marketed to reduce under-eye puffiness and fluid…

    Dermatology · Research Phase · Topical

    No lawful pathway
  17. 161

    Trylagen (Tripeptide-10 Complex)

    Trylagen is a proprietary cosmetic complex that incorporates Tripeptide-10 Citrulline along with other peptide and protein components, marketed to support…

    Dermatology · Research Phase · Topical

    No lawful pathway
  18. 162

    Myristoyl Pentapeptide-17

    Myristoyl Pentapeptide-17 is a lipopeptide composed of a pentapeptide sequence conjugated to myristic acid, intended to improve penetration into the skin and…

    Dermatology · Research Phase · Topical

    No lawful pathway
  19. 163

    Palmitoyl Tripeptide-1

    Palmitoyl Tripeptide-1 (also called Pal-GHK) is a synthetic lipopeptide in which the tripeptide glycyl-histidyl-lysine (GHK) is linked to palmitic acid to…

    Dermatology · Research Phase · Topical

    No lawful pathway
  20. 164

    Copper Peptide (Prezatide Copper Acetate)

    Prezatide copper acetate is the copper complex of the tripeptide glycyl-histidyl-lysine (GHK-Cu), a peptide originally isolated from human plasma. In…

    Dermatology · Investigational · Topical

    No lawful pathway
  21. 165

    Melitane (Acetyl Hexapeptide-1)

    Acetyl Hexapeptide-1 (trade name Melitane) is a synthetic hexapeptide cosmetic ingredient designed as a biomimetic of alpha-melanocyte-stimulating hormone…

    Dermatology · Research Phase · Topical

    No lawful pathway
  22. 166

    Thymogen (Glutamyl-Tryptophan)

    Thymogen is a synthetic dipeptide consisting of L-glutamic acid and L-tryptophan (L-Glu-L-Trp), developed in Russia as a synthetic analog of the thymus extract…

    Immune · Investigational · Subcutaneous injection, Topical

    No lawful pathway
  23. 167

    Thymostimulin (TP-1)

    Thymostimulin (TP-1) is a partially purified extract of calf thymus consisting of a mixture of polypeptides. It is thought to promote T-lymphocyte maturation…

    Immune · Investigational · Intramuscular injection, Subcutaneous injection

    No lawful pathway
  24. 168

    Splenopentin

    Splenopentin (SP-5) is a synthetic pentapeptide (Arg-Lys-Glu-Val-Tyr) corresponding to residues 32 to 36 of the splenic protein splenin. It differs from the…

    Immune · Investigational · Subcutaneous injection, Intravenous

    No lawful pathway
  25. 169

    Bursin

    Bursin is a tripeptide amide (Lys-His-Gly-NH2) originally isolated from the bursa of Fabricius in chickens, where it was described as a selective…

    Immune · Research Phase · Subcutaneous injection

    No lawful pathway
  26. 170

    Tuftsin

    Tuftsin is a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) released by enzymatic processing from the Fc domain of the immunoglobulin G heavy chain. It…

    Immune · Research Phase · Subcutaneous injection, Intravenous

    No lawful pathway
  27. 171

    Imuthiol (Diethyldithiocarbamate)

    Imuthiol (ditiocarb sodium) is the sodium salt of diethyldithiocarbamate, a small sulfur-containing molecule rather than a peptide, which was explored as an…

    Immune · Investigational · Intravenous, Oral

    No lawful pathway
  28. 172

    Alpha-MSH

    Alpha-melanocyte-stimulating hormone (alpha-MSH) is a 13-amino-acid peptide produced from proopiomelanocortin (POMC). Acting through melanocortin receptors, it…

    Immune · Investigational · Subcutaneous injection, Intravenous

    No lawful pathway
  29. 173

    Beta-Defensin 2

    Human beta-defensin 2 (hBD-2) is a 41-amino-acid cationic antimicrobial peptide first described in psoriatic skin and produced by epithelial cells in response…

    Immune · Research Phase · Topical, Subcutaneous injection

    No lawful pathway
  30. 174

    Beta-Defensin 3

    Human beta-defensin 3 (hBD-3) is a cationic antimicrobial peptide of roughly 45 amino acids. Unlike hBD-1 and hBD-2, it kills Gram-positive organisms such as…

    Immune · Research Phase · Topical, Subcutaneous injection

    No lawful pathway
  31. 175

    Granulysin

    Granulysin is an antimicrobial and cytolytic protein produced by human cytotoxic T lymphocytes and natural killer cells, and it is structurally related to…

    Immune · Research Phase · Intravenous, Subcutaneous injection

    No lawful pathway
  32. 176

    Serelaxin (Relaxin-2)

    Serelaxin is a recombinant form of human relaxin-2, a vasodilator peptide hormone that contributes to cardiovascular and renal adaptations during pregnancy. It…

    Cardiovascular · Investigational · Intravenous

    No lawful pathway
  33. 177

    Carperitide (h-ANP)

    Carperitide is a recombinant form of human atrial natriuretic peptide (alpha-human A-type natriuretic peptide), given intravenously. It activates guanylyl…

    Cardiovascular · Investigational · Intravenous

    No lawful pathway
  34. 178

    Ularitide (Urodilatin)

    Ularitide is a synthetic form of urodilatin, a natriuretic peptide produced in kidney tubular cells. Like other natriuretic peptides it acts on guanylyl…

    Cardiovascular · Investigational · Intravenous

    No lawful pathway
  35. 179

    Atrial Natriuretic Peptide (ANP)

    Atrial natriuretic peptide is a 28-amino acid hormone secreted mainly by atrial cardiomyocytes, one of the two classic cardiac natriuretic peptides along with…

    Cardiovascular · Investigational · Endogenous

    No lawful pathway
  36. 180

    Brain Natriuretic Peptide (BNP)

    Brain natriuretic peptide, despite its name, is a 32-amino acid hormone secreted predominantly by ventricular cardiomyocytes in response to increased wall…

    Cardiovascular · FDA Approved · Intravenous

    FDA-approved

Index · all 264 peptides, A–Z

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Peptide therapies discussed on this site may not be FDA-approved for all listed indications. Individual results vary. The Peptide Association does not prescribe, diagnose, or treat any medical condition. Clinicians in our network are independently licensed practitioners; the Association checks each clinician’s NPI record but does not employ or directly supervise these clinicians.

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